Ana Flores-Mireles Department of Biological Sciences, University of Notre Dame, USA, USA,
1 protocol

José Lemos Department of Oral Biology, University of Florida College of Dentistry, USA, USA,
3 protocols

Cristina Colomer-Winter
  • Sterility Assurance Scientist, Boehringer Ingelheim
Research focus
  • Microbiology
  • Bacteriology, Biometals, Stress Tolerance, Pathogenesis, Physiology, Virulence
  • 1 Author merit


PhD, University of Florida, 2018

Lab information

Disinfectant policy and validation, and regulatory policy on sterilization processes.


Colomer-Winter C, Flores-Mireles AL, Kundra S, Hultgren SJ, Lemos JA. "(p)ppGpp and CodY promote Enterococcus faecalis virulence in a murine model of catheter-associated urinary tract infection." mSphere 2019 4(4).pii:e00392-19.

Colomer-Winter C, Lemos JA, Flores-Mireles AL. “Biofilm assays on fibrinogen-coated silicone catheters and 96-well polystyrene plates.” Bio Protoc. 2019 Mar;9(6):e3196.

Colomer-Winter C, Gaca AO, Chuang-Smith ON, Lemos JA, Frank KL. “Cellular levels of (p)ppGpp differentially affect the pathogenesis of infective endocarditis in Enterococcus faecalis.” Microbiology 2018 Oct;164(10):1254-1265.

Colomer-Winter C, Flores-Mireles AL, Baker SP, Frank KL, Lynch AJL, Hultgren SJ, Kitten T, Lemos JA. “Manganese acquisition is essential for virulence of Enterococcus faecalis.” PLoS Pathog. 2018 Sep;14(9):e1007102.

Colomer-Winter C, Gaca AO, Lemos JA. “Association of metal homeostasis and (p)ppGpp regulation in the pathophysiology of Enterococcus faecalis.” Infect. Immun. 2017 Jul;85(7):e00260-17.

Gaca AO, Kudrin P, Colomer-Winter C, Beljantseva J, Liu K, Anderson B, Wang JD, Rejman D, Potrykus K, Cashel M, Hauryliuk V, Lemos JA. “From (p)ppGpp to (pp)pGpp: Characterization of regulatory effects of pGpp synthesized by the Small Alarmone Synthetase of Enterococcus faecalis.” J. Bacteriol. 2015

Gaca AO, Colomer-Winter C, Lemos JA. “Many means to a common end: the intricacies of (p)ppGpp metabolism and its control of bacterial homeostasis.” Mini-review. J. Bacteriol. 2015.

Frank KL, Colomer-Winter C, Grindle SM, Lemos JA, Schlievert PM, Dunny GM. “Transcriptome analysis of Enterococcus faecalis during mammalian infection shows cells undergo adaptation and exist in a Stringent Response state.” PLoS One. 2014 Dec 29;9(12):e115839.
1 Protocol published
Biofilm Assays on Fibrinogen-coated Silicone Catheters and 96-well Polystyrene Plates
Authors:  Cristina Colomer-Winter, José A. Lemos and Ana L. Flores-Mireles, date: 03/20/2019, view: 1177, Q&A: 0
Biofilm formation is a well-known bacterial strategy that protects cells from hostile environments. During infection, bacteria found in a biofilm community are less sensitive to antibiotics and to the immune response, often allowing them to colonize ...
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