Alessandro Didonna University of California, San Francisco
47 protocols

Chen Huei Leo Singapore University of Technology & Design
1 protocol

Jia Li SRI International
51 protocols

Mostafa Rahnama University of Kentucky Lexington
2 protocols

Reviewer
Sonal Arvind Patel
  • Research scientist, Fusion Pharmaceuticals
Research focus
  • Molecular biology
  • Obesity; aging; circadian clock; adipose tissue; metabolism; type 2 diabetes; Immuno-oncology

Education

Ph.D., Cleveland State University, 2016

Lab information

Dr. John Valliant

Publications

 Khapre RV, Patel SA, Kondratova AA, Chaudhary A, Velingkaar N, Antoch MP, Kondratov RV, Metabolic clock generates nutrient anticipation rhythms in mTOR signaling. Aging 2014 Aug; 6(8):675-89.
 Khapre RV, Kondratova AA, Patel S, Yuliya Dubrovsky, Wrobel M, Antoch MP, and Kondratov RV, BMAL1-dependent regulation of the mTOR signaling pathway delays aging. Aging 2014 Jan; 6(1):48-5.
 Patel SA, Velingkaar N, Kondratov RV, Transcriptional control of antioxidant defense by the circadian clock, Antioxidants & Redox Signaling 2014 Jun 20; 20(18):2997-3006.
 Patel SA, Chaudhari A, Gupta R, Velingkaar N, Kondratov RV, Calorie restriction-mediated lifespan extension by the clock protein BMAL1, FASEB J. 2016 Apr;30(4):1634-42. doi: 10.1096/fj.15-282475. Epub 2015 Dec 23.
 Patel SA., Velingkaar N., Makwana K., Chaudhari A., Kondratov RV., Calorie restriction regulates circadian clock genes expression through BMAL1 and CRY1 dependent mechanisms, Sci Rep. 2016 May 12;6:25970. doi: 10.1038/srep25970.
 Majumdar T., Dhar J., Patel S., Kondratov R., Barik S., Circadian transcription factor BMAL1 provides innate immunity against select RNA viruses, Innate Immun. 2017 Feb;23(2):147-154. doi: 10.1177/1753425916681075. Epub 2016 Dec 5.
 Chaudhari A., Gupta R., Patel SA., Velingkaar N., Kondratov RV., Cryptochromes regulate IGF-1 production and signaling through control JAK2 dependent STAT5B phosphorylation, Mol Biol Cell. 2017 Mar 15;28(6):834-842. doi: 10.1091/mbc. E16-08-0624. Epub 2017 Jan 18.
 Makwana K., Patel SA., Velingkaar N., Ebron JS., Shukla GC., and Kondratov RV., Aging and calorie restriction regulate the expression of miR-125a-5p and its target genes Stat3, Casp2 and Stard13, Aging (Albany NY). 2017 Jul 31;9(7):1825-1843. doi: 10.18632/aging.101270.
 Astafevy A., Patel SA., and Kondratov RV., Calorie restriction effects on circadian rhythms in gene expression are sex dependent, Sci Rep. 2017 Aug 29;7(1):9716. doi: 10.1038/s41598-017-09289-9.
 Sonal A. Patel, and Roman V. Kondratov, “Clock at the Core of Cancer Development”, Biology 2021, 10(2), 150; https://doi.org/10.3390/biology10020150.
 Wen Dai, Mayank Choubey, Sonal Patel and Lale Ozcan, “Adipocyte CaMKII deficiency improves obesity-associated glucose intolerance” (submitted in Molecular Metabolism)
3 Protocols reviewed
Isolation of Murine Primary Aortic Smooth Muscle Cells
Authors:  Max Ole Hubert, Juan Rodriguez-Vita, Lena Wiedmann and Andreas Fischer, date: 02/05/2021, view: 1004, Q&A: 0

Vascular smooth muscle cells (VSMCs) have been cultured for decades to study the role of these cells in cardiovascular disorders. The most common source of VSMCs is the rat aorta. Here we show the adaptation of this method to isolate and culture

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Development of the Deoxycorticosterone Acetate (DOCA)-salt Hypertensive Rat Model
Authors:  Nayara Pestana-Oliveira, David B. Nahey, Tim Johnson and John P. Collister, date: 08/05/2020, view: 2014, Q&A: 0
According to the World Health Organization (WHO), nearly 1.13 billion people worldwide have hypertension, a major factor responsible for premature death globally. The inherent multifactorial nature of hypertension makes its study difficult since the ...
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