Shaarika Sarasija
Research focus
  • Neuroscience
  • C. elegans, Presenilin, Calcium, Mitochondria, Neurodegeneration, Alzheimer's Disease


PhD, Albany Medical College, 2017

Lab information

I am the senior postdoctoral fellow in the Kenneth R. Norman Lab at Albany Medical College. My work focuses on non-amyloid hypothesis of Alzheimer's disease pathogenesis, with a an emphasis on aberrant calcium signaling and subsequent mitochondrial damage.

Sarasija S, Norman KR. Mutations in presenilin cause defects in mitochondrial calcium homeostasis and metabolic activity resulting in neurodegeneration. (Under peer-review at Elife)
Sarasija S, Norman KR. H2-DCFDA fluorescence measurement of ROS in in Caenorhabditis elegans. (Accepted at BioProtocol)
Sarasija S, Norman KR. Mitochondrial morphology analysis in in Caenorhabditis elegans. (Accepted at BioProtocol)
Sarasija S, Norman KR. A γ-Secretase Independent Role for Presenilin in Calcium Homeostasis Impacts Mitochondrial Function and Morphology in Caenorhabditis elegans. Genetics. 2015; 201(4):1453-66.
1 Protocol reviewed
Optical Clearing and Index Matching of Tissue Samples for High-resolution Fluorescence Imaging Using SeeDB2
Authors:  Meng-Tsen Ke and Takeshi Imai, date: 10/20/2018, view: 915, Q&A: 1
Tissue clearing techniques are useful for large-scale three-dimensional fluorescence imaging of thick tissues. However, high-resolution imaging deep inside tissues has been challenging, as it is extremely sensitive to light scattering and spherical ...
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