Edgar Soria-Gomez Faculty of Medicine and Nursery, University of the Basque Country
17 protocols

Sébastien Gillotin MSD, Discovery Research MRL
6 protocols

Reviewer
Shaarika Sarasija
  • Post-Doc, McGill University
Research focus
  • Cell biology
  • C. elegans, Presenilin, Calcium, Mitochondria, Neurodegeneration, Alzheimer's Disease, Aging

Education

PhD, Albany Medical College, 2017

Publications

https://www.ncbi.nlm.nih.gov/pmc/?term=Shaarika+Sarasija
1. Sarasija S, Norman KR. Measurement of oxygen consumption rates in intact Caenorhabditis elegans. J. Vis. Exp. 2019 (144), e59277

2. Sarasija S, Norman KR. Role of presenilin in mitochondrial oxidative stress and neurodegeneration in Caenorhabditis elegans. Antioxidants 2018 7(9), 111

3. Sarasija S, Norman KR. Mutations in presenilin cause defects in mitochondrial calcium homeostasis and metabolic activity resulting in neurodegeneration. eLIFE 2018 7: e33052.
Research Highlight: Clark N. Alternative model for alternative hypothesis. Lab Animal 2018 47(231)

4. Sarasija S, Norman KR. H2DCFDA fluorescence measurement of ROS in Caenorhabditis elegans. Bio-Protocol 2018 8(7)

5. Sarasija S, Norman KR. Mitochondrial morphology analysis in in Caenorhabditis elegans. Bio-Protocol 2018 8(7)

6. Sarasija S, Norman KR. A γ-secretase independent role for presenilin in calcium homeostasis impacts mitochondrial function and morphology in Caenorhabditis elegans. Genetics. 2015; 201(4):1453-66.
3 Protocols reviewed
Intracerebral Injection of Streptozotocin to Model Alzheimer Disease in Rats
Animal models have promoted meaningful contribution to science including Alzheimer’s disease (AD) research. Several animal models for AD have been used, most of them related to genetic mutations observed in familial AD. However, sporadic form of AD, ...
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Optical Stimulation and Electrophysiological Analysis of Regenerating Peripheral Axons
Authors:  Patricia J. Ward and Arthur W. English, date: 06/20/2019, view: 873, Q&A: 0
Although axons in the peripheral nervous system can regenerate, functional recovery after nerve injuries is poor. Activity-based therapies, such as exercise and electrical stimulation, enhance the regeneration of cut peripheral axons. Despite their ...
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