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Masanaga Muto Institute for Reproductive Health and Regenerative Medicine, Departments of Pathology & Laboratory Medicine and Pediatrics, University of Kansas Medical Center, USA, USA,
1 protocol

Damayanti Chakraborty Institute for Reproductive Health and Regenerative Medicine, Departments of Pathology & Laboratory Medicine and Pediatrics, University of Kansas Medical Center, USA, USA,
1 protocol

Michael J Soares
  • Institute for Reproductive Health and Regenerative Medicine, Departments of Pathology & Laboratory Medicine and Pediatrics, University of Kansas Medical Center, USA, USA,
  • 1 Author merit

Education

Ph.D., University of Hawaii, USA, 1981

Current position

University Distinguished Professor, Pathology, University of Kansas Medical Center, USA

Publications (since 2011)

  1. Soares, M. J., Iqbal, K. and Kozai, K. (2017). Hypoxia and placental development. Birth Defects Res 109(17): 1309-1329.
  2. Bu, P., Yagi, S., Shiota, K., Alam, S. M. K., Vivian, J. L., Wolfe, M. W., Rumi, M. A. K., Chakraborty, D., Kubota, K., Dhakal, P. and Soares, M. J. (2017). Origin of a rapidly evolving homeostatic control system programming testis function. J Endocrinol 234(2): 217-232.
  3. Rumi, M. A. K., Singh, P., Roby, K. F., Zhao, X., Iqbal, K., Ratri, A., Lei, T., Cui, W., Borosha, S., Dhakal, P., Kubota, K., Chakraborty, D., Vivian, J. L., Wolfe, M. W. and Soares, M. J. (2017). Defining the Role of Estrogen Receptor beta in the Regulation of Female Fertility. Endocrinology 158(7): 2330-2343.
  4. Chhibber, A., Woody, S. K., Karim Rumi, M. A., Soares, M. J. and Zhao, L. (2017). Estrogen receptor beta deficiency impairs BDNF-5-HT2A signaling in the hippocampus of female brain: A possible mechanism for menopausal depression. Psychoneuroendocrinology 82: 107-116.
  5. McGreal, S. R., Rumi, K., Soares, M. J., Woolbright, B. L., Jaeschke, H. and Apte, U. (2017). Disruption of Estrogen Receptor Alpha in Rats Results in Faster Initiation of Compensatory Regeneration Despite Higher Liver Injury After Carbon Tetrachloride Treatment. Int J Toxicol 36(3): 199-206.
  6. Dhakal, P. and Soares, M. J. (2017). Single-step PCR-based genetic sex determination of rat tissues and cells. Biotechniques 62(5): 232-233.
  7. Renaud, S. J., Scott, R. L., Chakraborty, D., Rumi, M. A. and Soares, M. J. (2017). Natural killer-cell deficiency alters placental development in rats. Biol Reprod 96(1): 145-158.
  8. Chakraborty, D., Cui, W., Rosario, G. X., Scott, R. L., Dhakal, P., Renaud, S. J., Tachibana, M., Rumi, M. A., Mason, C. W., Krieg, A. J. and Soares, M. J. (2016). HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia. Proc Natl Acad Sci U S A 113(46): E7212-E7221.
  9. Soares, M. J. and Vivian, J. L. (2016). Tipping the balance toward trophoblast development. Proc Natl Acad Sci U S A 113(19): 5144-5146.
  10. Bu, P., Alam, S. M., Dhakal, P., Vivian, J. L. and Soares, M. J. (2016). A Prolactin Family Paralog Regulates Placental Adaptations to a Physiological Stressor. Biol Reprod 94(5): 107.
  11. Imakawa, K., Dhakal, P., Kubota, K., Kusama, K., Chakraborty, D., Karim Rumi, M. A. and Soares, M. J. (2016). CITED2 modulation of trophoblast cell differentiation: insights from global transcriptome analysis. Reproduction 151(5): 509-516.
  12. Kubota, K., Cui, W., Dhakal, P., Wolfe, M. W., Rumi, M. A., Vivian, J. L., Roby, K. F. and Soares, M. J. (2016). Rethinking progesterone regulation of female reproductive cyclicity. Proc Natl Acad Sci U S A 113(15): 4212-4217.
  13. Ilekis, J. V., Tsilou, E., Fisher, S., Abrahams, V. M., Soares, M. J., Cross, J. C., Zamudio, S., Illsley, N. P., Myatt, L., Colvis, C., Costantine, M. M., Haas, D. M., Sadovsky, Y., Weiner, C., Rytting, E. and Bidwell, G. (2016). Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. Am J Obstet Gynecol 215(1 Suppl): S1-S46.
  14. Dhakal, P., Rumi, M. A., Kubota, K., Chakraborty, D., Chien, J., Roby, K. F. and Soares, M. J. (2015). Neonatal Progesterone Programs Adult Uterine Responses to Progesterone and Susceptibility to Uterine Dysfunction. Endocrinology 156(10): 3791-3803.
  15. Renaud, S. J., Chakraborty, D., Mason, C. W., Rumi, M. A., Vivian, J. L. and Soares, M. J. (2015). OVO-like 1 regulates progenitor cell fate in human trophoblast development. Proc Natl Acad Sci U S A 112(45): E6175-6184.
  16. Kubota, K., Kent, L. N., Rumi, M. A., Roby, K. F. and Soares, M. J. (2015). Dynamic Regulation of AP-1 Transcriptional Complexes Directs Trophoblast Differentiation. Mol Cell Biol 35(18): 3163-3177.
  17. Alam, S. M., Konno, T. and Soares, M. J. (2015). Identification of target genes for a prolactin family paralog in mouse decidua. Reproduction 149(6): 625-632.
  18. PrabhuDas, M., Bonney, E., Caron, K., Dey, S., Erlebacher, A., Fazleabas, A., Fisher, S., Golos, T., Matzuk, M., McCune, J. M., Mor, G., Schulz, L., Soares, M., Spencer, T., Strominger, J., Way, S. S. and Yoshinaga, K. (2015). Immune mechanisms at the maternal-fetal interface: perspectives and challenges. Nat Immunol 16(4): 328-334.
  19. Soares, M. J., Chakraborty, D., Kubota, K., Renaud, S. J. and Rumi, M. A. (2014). Adaptive mechanisms controlling uterine spiral artery remodeling during the establishment of pregnancy. Int J Dev Biol 58(2-4): 247-259.
  20. Rumi, M. A., Dhakal, P., Kubota, K., Chakraborty, D., Lei, T., Larson, M. A., Wolfe, M. W., Roby, K. F., Vivian, J. L. and Soares, M. J. (2014). Generation of Esr1-knockout rats using zinc finger nuclease-mediated genome editing. Endocrinology 155(5): 1991-1999.
  21. Renaud, S. J., Kubota, K., Rumi, M. A. and Soares, M. J. (2014). The FOS transcription factor family differentially controls trophoblast migration and invasion. J Biol Chem 289(8): 5025-5039.
  22. Soares, M. J. (2014). Embryo implantation - coordination of maternal and embryonic adaptations. Int J Dev Biol 58(2-4): 71-74.
  23. Holloway, A. C., Salomon, A., Soares, M. J., Garnier, V., Raha, S., Sergent, F., Nicholson, C. J., Feige, J. J., Benharouga, M. and Alfaidy, N. (2014). Characterization of the adverse effects of nicotine on placental development: in vivo and in vitro studies. Am J Physiol Endocrinol Metab 306(4): E443-456.
  24. Kwok, S. C., Chakraborty, D., Soares, M. J. and Dai, G. (2013). Relative expression of proprotein convertases in rat ovaries during pregnancy. J Ovarian Res 6(1): 91.
  25. Imakawa, K., Nakagawa, S. and Kusama, K. (2016). Placental Development and Endogenous Retroviruses. Uirusu 66(1): 1-10.
  26. Hong, J., He, H., Bui, P., Ryba-White, B., Rumi, M. A., Soares, M. J., Dutta, D., Paul, S., Kawamata, M., Ochiya, T., Ying, Q. L., Rajanahalli, P. and Weiss, M. L. (2013). A focused microarray for screening rat embryonic stem cell lines. Stem Cells Dev 22(3): 431-443.
  27. Chakraborty, D., Rumi, M. A. and Soares, M. J. (2012). NK cells, hypoxia and trophoblast cell differentiation. Cell Cycle 11(13): 2427-2430.
  28. Shankar, K., Zhong, Y., Kang, P., Blackburn, M. L., Soares, M. J., Badger, T. M. and Gomez-Acevedo, H. (2012). RNA-seq analysis of the functional compartments within the rat placentation site. Endocrinology 153(4): 1999-2011.
  29. Soares, M. J., Chakraborty, D., Karim Rumi, M. A., Konno, T. and Renaud, S. J. (2012). Rat placentation: an experimental model for investigating the hemochorial maternal-fetal interface. Placenta 33(4): 233-243.
  30. Hayakawa, K., Nakanishi, M. O., Ohgane, J., Tanaka, S., Hirosawa, M., Soares, M. J., Yagi, S. and Shiota, K. (2012). Bridging sequence diversity and tissue-specific expression by DNA methylation in genes of the mouse prolactin superfamily. Mamm Genome 23(5-6): 336-345.
  31. Kent, L. N., Ohboshi, S. and Soares, M. J. (2012). Akt1 and insulin-like growth factor 2 (Igf2) regulate placentation and fetal/postnatal development. Int J Dev Biol 56(4): 255-261.
  32. Asanoma, K., Kubota, K., Chakraborty, D., Renaud, S. J., Wake, N., Fukushima, K., Soares, M. J. and Rumi, M. A. (2012). SATB homeobox proteins regulate trophoblast stem cell renewal and differentiation. J Biol Chem 287(3): 2257-2268.
  33. Soares, M. J., Chakraborty, D., Renaud, S. J., Kubota, K., Bu, P., Konno, T. and Rumi, M. A. (2012). Regulatory pathways controlling the endovascular invasive trophoblast cell lineage. J Reprod Dev 58(3): 283-287.
  34. Kent, L. N., Rumi, M. A., Kubota, K., Lee, D. S. and Soares, M. J. (2011). FOSL1 is integral to establishing the maternal-fetal interface. Mol Cell Biol 31(23): 4801-4813.
  35. Chakraborty, D., Rumi, M. A., Konno, T. and Soares, M. J. (2011). Natural killer cells direct hemochorial placentation by regulating hypoxia-inducible factor dependent trophoblast lineage decisions. Proc Natl Acad Sci U S A 108(39): 16295-16300.
  36. Konno, T., Rempel, L. A., Rumi, M. A., Graham, A. R., Asanoma, K., Renaud, S. J. and Soares, M. J. (2011). Chromosome-substituted rat strains provide insights into the genetics of placentation. Physiol Genomics 43(15): 930-941.
  37. Dai, G., Bustamante, J. J., Zou, Y., Myronovych, A., Bao, Q., Kumar, S. and Soares, M. J. (2011). Maternal hepatic growth response to pregnancy in the mouse. Exp Biol Med (Maywood) 236(11): 1322-1332.
  38. Al-Khan, A., Aye, I. L., Barsoum, I., Borbely, A., Cebral, E., Cerchi, G., Clifton, V. L., Collins, S., Cotechini, T., Davey, A., Flores-Martin, J., Fournier, T., Franchi, A. M., Fretes, R. E., Graham, C. H., Godbole, G., Hansson, S. R., Headley, P. L., Ibarra, C., Jawerbaum, A., Kemmerling, U., Kudo, Y., Lala, P. K., Lassance, L., Lewis, R. M., Menkhorst, E., Morris, C., Nobuzane, T., Ramos, G., Rote, N., Saffery, R., Salafia, C., Sarr, D., Schneider, H., Sibley, C., Singh, A. T., Sivasubramaniyam, T. S., Soares, M. J., Vaughan, O., Zamudio, S. and Lash, G. E. (2011). IFPA Meeting 2010 Workshops Report II: Placental pathology; trophoblast invasion; fetal sex; parasites and the placenta; decidua and embryonic or fetal loss; trophoblast differentiation and syncytialisation. Placenta 32 Suppl 2: S90-99.
  39. Asanoma, K., Rumi, M. A., Kent, L. N., Chakraborty, D., Renaud, S. J., Wake, N., Lee, D. S., Kubota, K. and Soares, M. J. (2011). FGF4-dependent stem cells derived from rat blastocysts differentiate along the trophoblast lineage. Dev Biol 351(1): 110-119.
  40. Renaud, S. J., Karim Rumi, M. A. and Soares, M. J. (2011). Review: Genetic manipulation of the rodent placenta. Placenta 32 Suppl 2: S130-135.
  41. Renaud, S. J. and Soares, M. J. (2011). Strategies for investigating hemochorial placentation. In: Gupta, R. C. (Ed). Handbook of Reproductive and Developmental Toxicology, Elsevier, pp: 1029-1038.
  42. Lafontaine, L., Chaudhry, P., Lafleur, M. J., Van Themsche, C., Soares, M. J. and Asselin, E. (2011). Transforming growth factor Beta regulates proliferation and invasion of rat placental cell lines. Biol Reprod 84(3): 553-559.
1 Protocol published
Ex vivo Trophoblast-specific Genetic Manipulation Using Lentiviral Delivery
Authors:  Damayanti Chakraborty, Masanaga Muto and Michael J. Soares, date: 12/20/2017, view: 1656, Q&A: 0
In this protocol report, we describe a lentiviral gene delivery technique for genetic modification of the rat trophoblast cell lineage. Lentiviral packaged gene constructs can be efficiently and specifically delivered to the trophoblast cell lineage ...