Alessandro Didonna University of California, San Francisco
46 protocols

Alexandros Alexandratos National and Kapodistrian University of Athens
42 protocols

Gal Haimovich Molecular Genetics, Weizmann Institute of Science, Israel
95 protocols

Juan Facundo Ayala Instituto de Nanociencia y Nanotecnología
23 protocols

  • Research scientist, Buck Institute for Research on Aging
Research focus
  • Molecular biology
  • Infectious Disease
    Innate Immunity
    Advanced glycation
    Metabolic disorders


Ph.D, Alagappa University, 2013

1. Durai S, Yiyong L, Phillip W, Chia-Hui C, David L, and Jingru S (2019) Neuronal GPCR NPR-8 regulates C. elegans defense against pathogen infection. Science Advances. 5, eaaw4717.
2. Durai S *, Chung-Hsiang Y *, Phillip W, Yiyong L and Jingru S (2018) Octopaminergic Signaling Mediates Neural Regulation of Innate Immunity in Caenorhabditis elegans. mBio 9: e01645-18
(*Equal contribution).
3. Durai S, Yugantak R G, Murugananthkumar R, Senthilkumaran B (2018) Enterotoxic effects of Aeromonas hydrophila infection in the catfish, Clarias gariepinus: Biochemical, histological and proteome analyses. Veterinary Immunology and Immunopathology 204, 1-10.
4. Yiyong L, Durai S, and Jingru S (2016) Neuronal GPCR OCTR-1 regulates innate immunity by controlling protein synthesis in Caenorhabditis elegans Scientific Reports. 6, 36832.
5. Yugantak R G, Durai S, Monica K, Deepa S, Senthilkumaran B and Basavaraju Y (2016) Effect of copper nanoparticles exposure in the physiology of the common carp (Cyprinus carpio): Biochemical, histological and proteomic approaches. Aquaculture and Fisheries 1, 15-23.
6. Vigneshkumar B, Durai S, Suman K and Balamurugan K (2016) Proteome Analysis Reveals Translational Inhibition of Caenorhabditis elegans enhances susceptibility to Pseudomonas aeruginosa PAO1 pathogenesis. Journal of Proteomics 145, 141–152.
7. JebaMercy G*, Durai S*, Prithika U, Marudhupandiyan S, Pushpanjali D, Suman K and Balamurugan K (2016) Role of DAF-21 protein in Caenorhabditis elegans immunity against Proteus mirabilis infection. (*Equal contribution) Journal of Proteomics 145, 81–90.
8. Durai S, Nirpendra S, Suman K, and Balamurugan K, (2014) Proteomic investigation in Caenorhabditis elegans against Vibrio alginolyticus infection revealed regulation of cellular homeostasis proteins and their role in supporting the innate immune system, Proteomics 14:1820-32.
9. Durai S, Vigneshwari L and Balamurugan K (2013). Caenorhabditis elegans based in vivo screening of bioactive from marine sponge-associated bacteria against Vibrio alginolyticus Journal of Applied Microbiology 115 (6): 1329-1342.
10. Durai S, Pandian SK and Balamurugan K (2011). Changes in Caenorhabditis elegans exposed to Vibrio parahaemolyticus. Journal of Microbiology and Biotechnology. 21(10), 1026–1035.
11. Durai S, Pandian SK and Balamurugan K (2011). Establishment of Caenorhabditis elegans infection model for Vibrio alginolyticus. Journal of Basic Microbiology. 51(3):243-52.
3 Protocols reviewed
Isolation and Imaging of His- and RFP-tagged Amyloid-like Proteins from Caenorhabditis elegans by TEM and SIM
Authors:  Amberley D. Stephens, Meng Lu and Gabriele S. Kaminski Schierle, date: 11/05/2019, view: 2020, Q&A: 0
In our recently published paper, we highlight that during normal aging of C. elegans age-dependent aggregates of proteins form and lead to functional decline of tissues. The protocol described here details the isolation of two proteins from ...
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Pentylenetetrazole (PTZ)-induced Convulsion Assay to Determine GABAergic Defects in Caenorhabditis elegans
Authors:  Shruti Thapliyal and Kavita Babu, date: 09/05/2018, view: 3409, Q&A: 0
Pentylenetetrazole (PTZ) is a GABAA receptor antagonist and is used to monitor presynaptic defects in the release of the inhibitory neurotransmitter GABA. PTZ is a competitive inhibitor of GABA, and prevents binding of GABA on the GABAA ...
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