Emily Cope Northern Arizona University
7 protocols

Geoffrey Lau City University of Hong Kong
8 protocols

Qing Yan Duke University
3 protocols

Sofiane El-Kirat-Chatel The National Center for Scientific Research
3 protocols

Juan Facundo Rodriguez Ayala
  • Research associate, National University of Rosario
Research focus
  • Microbiology
  • C. elegans, aging, B. subtilis, Probiotic, Neurobiology


PhD, PROBIOL, National University of Cuyo, 2012

Lab information

Dr. Roberto Grau's lab


1) Facundo Rodriguez Ayala, Carlos Bauman, Cecilia Leñini, Marco Bartolini, Sebastián Cogliati, Federico Argañaraz, and Roberto Grau (2017) “Induction of the host complement system by probiotic Bacillus subtilis”. Molecular Microbiology (sent).
2) Sebastián Cogliati, Facundo Rodriguez Ayala*, Carlos Bauman, Cecilia Leñini, Marco Bartolini, Juan Manuel Villalba, Federico Argañaraz and Roberto Grau (2017). “Determination of NO and CSF Levels Produced by Bacillus subtilis”. BioProtocol Vol 7, Iss 13, doi:10.21769/BioProtoc.2379 (Corresponding author).
3) Facundo Rodriguez Ayala*, Sebastián Cogliati, Carlos Bauman, Cecilia Leñini, Marco Bartolini, Juan Manuel Villalba, Federico Argañaraz and Roberto Grau (2017). “Culturing Bacteria from Caenorhabditis elegans Gut to Assess Colonization Proficiency”. BioProtocol Vol 7, Iss 12, Jun 20, doi:10.21769/BioProtoc.2345 (Corresponding author).
4) Ayala FR, Bauman C, Cogliati S, Leñini C, Bartolini M, Grau R (2017). “Microbial flora, probiotics, Bacillus subtilis and the search for a long and healthy human longevity.” Microb Cell. 16;4(4):133-136. doi: 10.15698/mic2017.04.569.
5) Rodriguez Ayala F, Bauman C, Bartolini M, Saball E, Salvarrey M, Leñini C, Cogliati S, Strauch M, Grau R. (2017). “Transcriptional regulation of adhesive properties of Bacillus subtilis to extracellular matrix proteins through the fibronectin-binding protein YloA”. Mol Microbiol. 104(5):804-821. doi: 10.1111/mmi.13666.
6) Facundo Rodriguez Ayala*; Verónica Donato*; Sebastián Cogliati*; Juan Gabriel Costa; Cecilia Leñini and Roberto Grau (2017). “Bacillus subtilis biofilm extends Caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway.” Nat Commun. 30; 8:14332.
7) Sebastián Cogliati; Juan Gabriel Costa; Facundo Rodriguez Ayala; Verónica Donato and Roberto Grau (2016). “Bacterial spores and its relatives as agents of mass destruction”. J Bioterror Biodef, 7:1.
8) Rodriguez, F; Zanetti, MN; Mayorga LS; Tomes CN (2012). ˮMunc18 controls protein complex assembly during human sperm acrosomal exocytosis”. J Biol Chem. 21; 287(52):43825-39; doi: 10.1074/jbc.M112.409649.
9) Rodriguez, F; Bustos, MA; Zanetti, MN; Ruete, C; Mayorga LS; Tomes CN (2011). ˮα-SNAP prevents docking of the acrosome because sequesters monomeric syntaxin” PLoS One; 6(7):e21925; doi: 10.1371/journal.pone.0021925.
10) Bátiz LF, De BlasGA, Michaut MA, Ramírez AR, Rodriguez F, Ratto MH, Oliver C, Tomes CN, Rodríguez EM, and Mayorga LS (2009). ˮA point mutation of aSNAP causes impaired acrosome reaction and reduced male fertilityˮ. PLoS ONE. 4(3):e4963; doi: 10.1371/journal.pone.0004963.

3 Protocols reviewed
Measurement of ROS in Caenorhabditis elegans Using a Reduced Form of Fluorescein
Authors:  Shaarika Sarasija and Kenneth R. Norman, date: 04/05/2018, view: 632, Q&A: 0
Oxidative stress is implicated in the pathogenesis of various neurodegenerative diseases, including Alzheimer’s disease. Oxidative stress is a result of a disruption of the equilibrium between antioxidants and oxidants, in favor of oxidants. Since ...
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Assessing Prepulse Inhibition of Startle in Mice
Authors:  Christina Ioannidou, Giovanni Marsicano and Arnau Busquets-Garcia, date: 04/05/2018, view: 637, Q&A: 0
Animal models are an important tool for studying neuropsychiatric disorders. However, a major challenge for researchers working with laboratory rodents is trying to reproduce ‘core’ symptoms of complex human disorders such as schizophrenia. Despite ...
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