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Beat Bornhauser Department of Oncology and Children’s Research Center, University Children's Hospital Zurich, Switzerland
 1 protocol

Jean-Pierre Bourquin Department of Oncology and Children’s Research Center, University Children’s Hospital Zurich, Switzerland
 1 protocol

Adriano Aguzzi Institute of Neuropathology, University Hospital of Zurich, Switzerland
 1 protocol

Pawel Pelczar Institute of Laboratory Animal Science, University of Zurich, Switzerland
 1 protocol

Lena Behrmann
  • Department of Oncology and Children’s Research Center, University Children's Hospital Zurich, Switzerland
Research focus
  • Molecular biology
  • 1 Author merit
1 Protocol published
Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9
Authors:  Lena Behrmann, Scott McComb, Júlia Aguadé-Gorgorió, Yun Huang, Mario Hermann, Pawel Pelczar, Adriano Aguzzi, Jean-Pierre Bourquin and Beat C. Bornhauser, date: 04/05/2017, view: 14437, Q&A: 0
CRISPR-Cas9 based knockout strategies are increasingly used to analyze gene function. However, redundancies and overlapping functions in biological signaling pathways can call for generating multi-gene knockout cells, which remains a relatively ...
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