Jonathan Coquet Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, Sweden
1 protocol
Alka Mehra Institute of Genomics and Integrative Biology
40 protocols

Kate Hannan The Australian National University
15 protocols

Lokesh Kalekar eGenesis Inc
18 protocols

Murugappan Sathappa Broad Institute
4 protocols

Reviewer
Chris Tibbitt
  • Post-Doc, Karolinska Institutet
Research focus
  • Immunology
  • - T helper cell differentiation
    - ILC differentiation
    - Allergy
    -Single Cell RNA Sequencing
  • 1 Author merit

Education

PhD, Newcastle University, 2015

Lab information

Jenny Mjösberg Lab
https://ki.se/en/medh/jenny-mjosberg-group

Publications

https://scholar.google.se/citations?user=lJUUlIAAAAAJ&hl=en
1) Tibbitt CA*, Stark JM*, Martens L, Ma J, Mold JE, Deswarte K, Olinyk G, Feng X, Lambrecht BN, De Bleser P, Nylen S, Hammad H, Aresnian Henriksson M, Saeys Y & Coquet JM. (2019). 'Single-cell RNA sequencing of the T helper cell response to house dust mites defines a distinct gene expression signature in airway Th2 cells' Immunity. 51 (1). *Joint first-author.

2) Chen T*, Tibbitt CA*, Feng X, Stark JM, Rohrbeck L, Rausch L, Sedimbi SK, Karlsson MCI, Lambrecht BN, Karlsson Hedestam GB, Hendriks RW, Chambers BJ, Nylén S, Coquet JM. (2017). ‘PPAR-γ promotes type 2 immune responses in allergy and nematode infection’. Science Immunology. 2 (9).
*Joint first-author.

3) Tibbitt C, Falconer J, Stoop J, van Eden W, Robinson JH, Hilkens CM. (2016). 'Citrullinated aggrecan enhances Th17 generation through alteration to STAT3/5 balance'. European Journal of Immunology. 46 (7). 1633-1643.

4) Tibbitt CA and Coquet JM. (2016). ‘House Dust Mite Extract and Cytokine Instillation of the Airways and Subsequent Analysis’. Bio-protocols. 6 (14). e1875.

5) Stoop JN, Tibbitt CA, van Eden W, Robinson JH, Hilkens CM. (2013). 'The choice of adjuvant determines the cytokine profile of T cells in proteoglycan-induced arthritis but does not influence disease severity'. Immunology. 138 (1). 68-75.
1 Protocol published
对小鼠气道滴注尘螨提取物和细胞因子进行炎症分析
Authors:  Chris Tibbitt and Jonathan M. Coquet, date: 07/20/2016, view: 10055, Q&A: 1
Asthma is a complex disease of the airways primarily mediated by T helper 2 cells and innate lymphoid type 2 cells (Licona et al.,2013). Mice do not develop spontaneous asthma and therefore models have been developed for the assessment of ...
5 Protocols reviewed
Using the Cecal Ligation and Puncture Model of Sepsis to Induce Rats to Multiple Organ Dysfunction

Sepsis is a dysregulated hyperinflammatory disease caused by infection. Sepsis leads to multiple organ dysfunction syndrome (MODS), which is associated with high rates of mortality. The cecal ligation and puncture (CLP) model has been widely used in

...
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In vitro Differentiation of Thymic Treg Cell Progenitors to Mature Thymic Treg Cells
Authors:  David L. Owen and Michael A. Farrar, date: 08/20/2019, view: 2420, Q&A: 0
Thymic Treg cell differentiation occurs via a two-step process. Step one generates Treg cell progenitors (TregP) and is driven by strong TCR interactions with antigens presented in the thymus. Step two is initiated ...
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