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Coauthors
Garrett Berry Gene Therapy Center, The University of North Carolina at Chapel Hill, USA
1 protocol

Gary Whittaker Department of Microbiology and Immunology, Cornell University, United States
2 protocols

Yueting Zhang Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, USA
1 protocol
Coreviewers
Arsalan Daudi University of California
156 protocols

Daan Swarts Department of Biochemistry, University of Zurich, Switzerland
9 protocols

David Paul Medical Research Council
9 protocols

Ehsan Kheradpezhouh Australian National University
7 protocols

Editor
Longping Victor Tse
  • Post-Doc, University of North Carolina at Chapel Hill
Research focus
  • Gene Therapy
  • Gene Delivery
    Vector Engineering
    Infectious Diseases
  • 2 Author merit

Education

PhD, Cornell University, 2014

Lab information

Aravind Asokan

2 Protocols published
Virus Binding and Internalization Assay for Adeno-associated Virus
Authors:  Garrett E. Berry and Longping V. Tse, date: 01/20/2017, view: 3370, Q&A: 0
The binding and internalization of adeno-associated virus (AAV) is an important determinant of viral infectivity and tropism. The ability to dissect these two tightly connected cellular processes would allow better understanding and provide insight ...
Immunoplaque Assay (Influenza Virus)
Authors:  Longping V. Tse, Yueting Zhang and Gary R. Whittaker, date: 11/05/2013, view: 10561, Q&A: 0
Despite developed long time ago, plaque assay is still the gold standard for viral titer quantification in modern virology. The standard crystal violet-based plaque assay relies on virus’ ability to induce cytopathic effect (CPE) which limits the ...
5 Protocols reviewed
Mouse Model of Dengue Virus Infection with Serotypes 1 and 2 Clinical Isolates
Authors:  Satoru Watanabe , Kitti Wing Ki Chan and Subhash G. Vasudevan, date: 12/05/2016, view: 3516, Q&A: 0
Dengue is a global public health threat caused by infection with any of the 4 related dengue virus serotypes (DENV1-4). Clinical manifestations range from self-limiting febrile illness, known as dengue fever (DF), to life-threatening severe ...
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Protein Expression, Purification and Crystallization of the Sxl-Unr-msl2 Ribonucleoprotein Complex
Authors:  Janosch Hennig and Michael Sattler, date: 09/05/2016, view: 3153, Q&A: 0
This protocol describes the expression, purification and crystallization of a ternary protein-protein-RNA complex, consisting of the two RNA recognition motifs (RRMs) of Sex-lethal (Sxl), the first of five cold shock domains of Upstream-of-N-Ras ...
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11 Protocols edited
A Lentiviral Pseudotype ELLA for the Measurement of Antibodies Against Influenza Neuraminidase
Authors:  Fabrizio Biuso, George Carnell, Emanuele Montomoli and Nigel Temperton, date: 07/20/2018, view: 69, Q&A: 0
This protocol describes the rapid and safe production of lentiviral pseudotypes characterized by a lentiviral core containing a reporter, in conjunction with avian influenza haemagglutinin (HA) and human neuraminidase (NA) glycoproteins on the ...
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Nab Escaping AAV Mutants Isolated from Mouse Muscles
Authors:  Zheng Chai, R. Jude Samulski and Chengwen Li, date: 05/05/2018, view: 580, Q&A: 0
Neutralizing antibodies (Nabs) are a major challenge in clinical trials of adeno-associated virus (AAV) vector gene therapy, because Nabs are able to inhibit AAV transduction in patients. We have successfully isolated several novel Nab-escaped AAV ...
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