Cancer Biology

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    Protocols in Current Issue
    Detection of ALT Associated Promyelocytic Leukemia Nuclear Bodies (APBs) by Immunofluorescence-FISH (IF-FISH)
    Authors:  Siamak A. Kamranvar and Maria G. Masucci, date: 12/05/2014, view: 9903, Q&A: 0
    [Abstract] The activation of functions that counteract the physiological shortening of telomeres in rapidly proliferating cell is prerequisite for the progression of cancer cells to full malignancy (Collado et al., 2007). In most human cancers, the length of telomere is maintained through up-regulation of telomerase whereas a telomerase-independent ...



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