Armando Parodi Fundación Instituto Leloir Buenos Aires
1 protocol

Ariel Weisz Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales Buenos Aires
1 protocol

Giovanna Gallo Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales and Consejo Nacional de investigaciones Científicas y Técnicas (CONICET) Buenos Aires
1 protocol

Ayelen Valko Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales and Consejo Nacional de investigaciones Científicas y Técnicas (CONICET) Buenos Aires
1 protocol

Cecilia D'Alessio
  • Faculty, Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales Buenos Aires
Research focus
  • We are interested on understanding the molecular basis of Congenital Disorders of Glycosylation, using fission yeast mutants as a model organisms, and focusing on basic cell glycobiology underlying processes of the diseases. In particular, we focus in N-glycosylation and in the early steps of N-glycan processing.
    We also use yeasts to express recombinant proteins, to perform functional complementation studies, to engineer strains to be used in bioremediation processes and other biotechnology applications.
  • 1 Author merit
1 Protocol published
Analysis of Lipid-linked Oligosaccharides Synthesized in vivo in Schizosaccharomyces pombe

Dolichol diphosphate-linked oligosaccharides (LLO) are the sugar donors in N-glycosylation, a fundamental protein post-translational modification of the eukaryotic secretory pathway. Defects in LLO biosynthesis produce human Congenital

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