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Preprint

Synthesis of CDP-steroid conjugates

JO James M. Olson

Last updated date: Apr 21, 2023 Views: 28 Forks: 0

original An abbreviated version of this protocol was published in Science Translational Medicine in Mar, 2020
A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure
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The protocol can be downloaded without paywall from Science Translational Medicine. It is in the supplemental materials.  If you have more questions, please email emily.girard@seattlechildrens.org

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How to cite：
Readers should cite both the Bio-protocol preprint and the original research article where this protocol was used:
  1. Olson, J(2023). Synthesis of CDP-steroid conjugates. Bio-protocol Preprint. bio-protocol.org/prep2215.
  2. Sangar, M. L. C., Girard, E. J., Hopping, G., Yin, C., Pakiam, F., Brusniak, M., Nguyen, E., Ruff, R., Gewe, M. M., Byrnes-Blake, K., Nairn, N. W., Miller, D. M., Mehlin, C., Strand, A. D., Mhyre, A. J., Correnti, C. E., Strong, R. K., Simon, J. A. and Olson, J. M.(2020). A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure . Science Translational Medicine 12(533). DOI: 10.1126/scitranslmed.aay1041

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