All codes used in the paper are available at https://github.com/biocq/DORGE.
Complete codes (Rmd notebook file) and data to test the DORGE machine-learning model used in the DORGE paper can be found in DORGE_tool_reproduce.zip. For your convenience, illustrative codes of the DORGE machine-learning model used in the DORGE paper can be found at https://biocq.github.io/DORGE/DORGE.html. An online video that explains the code is available at https://www.youtube.com/watch?v=Pk8ZqoHK8zk.
Codes to reproduce the results in DORGE paper can be found at https://github.com/biocq/DORGE_codes.
Codes to visualize the prediction by Shiny app can be found at the DORGE_shiny folder in the website indicated above.
The auxiliary datasets that are necessary to process raw data were hosted at Figshare https://figshare.com/projects/DORGE_Discovery_of_Oncogenes_and_Tumor_SuppressoR_Genes_Using_Genetic_and_Epigenetic_Features/78249, please note they are extreme large.
Further details are available at https://github.com/biocq/DORGE_codes.
Do you have any questions about this protocol?
Post your question to gather feedback from the community. We will also invite the authors of this
article to respond.