Abstract
Methods for the isolation and characterization of mononuclear phagocytes from the kidneys of mice with SLE are essential to understand the patho-physiology of the disease. Activation of these cells is associated with the onset of clinical disease in mice and infiltration with these cells is associated with poor prognosis in humans.An analysis of the function of these cells should lead to a better understanding of the inflammatory processes that lead to renal impairment in SLE and other renal inflammatory diseases.
Materials and Reagents
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Acknowledgments
This work was supported by the NY SLE foundation to RB and National Institutes of Health RO1 DK085241-01 for AD.
References
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