Cancer Biology


    Protocols in Current Issue
    Genome-Wide siRNA Screen for Anti-Cancer Drug Resistance in Adherent Cell Lines
    Authors:  Elza C. de Bruin, Ming Jiang, Michael Howell and Julian Downward, date: 05/20/2015, view: 11523, Q&A: 0
    [Abstract] The expression of genes is frequently manipulated in cell lines to study their cellular functions. The use of exogenous small Interfering RNAs (siRNAs) is a very efficient technique to temporarily downregulate the expression of genes of interest [reviewed by Hannon and Rossi (2004)]. A genome-wide siRNA library allows the user to study both the ...

    We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.