Hypoxia Studies with Pimonidazole in vivo
Authors: Kristina Y. Aguilera and Rolf A. Brekken, date: 10/05/2014, view: 21073, Q&A: 0
Therapy-induced hypoxia drives changes in the tumor microenvironment that contribute to the poor response to therapy. Hypoxia is capable of driving the expression and/or activation of specific signaling cascades (e.g., c-Met, Axl, CTGF), the recruitment of tumor promoting immune cells, and the induction of cell survival pathways including ...
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