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Stephan Gasser

Departments of Microbiology and Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore

Personal information

Education

Ph.D. in Sciences, ISREC, University of Lausanne, 2001

Current position

Assistant Professor, Immunology Programme, Department of Microbiology, National University of Singapore

Publications (since 2005)

  1. Lam R.A., Chwee J.Y., Le Bert N., Sauer M., Pogge von Strandmann E., and Gasser S. (2013). Regulation of Self-Ligands for Activating Natural Killer Cell Receptors. Ann. of Med. In press.
  2. Croxford, J. L., Tang, M. L., Pan, M. F., Huang, C. W., Kamran, N., Phua, C. M., Chng, W. J., Ng, S. B., Raulet, D. H. and Gasser, S. (2013). ATM-dependent spontaneous regression of early Emu-myc-induced murine B-cell leukemia depends on natural killer and T cells. Blood 121(13): 2512-2521.
  3. Kamran, N., Takai, Y., Miyoshi, J., Biswas, S. K., Wong, J. S. and Gasser, S. (2013). Toll-like receptor ligands induce expression of the costimulatory molecule CD155 on antigen-presenting cells. PLoS ONE 8(1): e54406.
  4. Raulet, D. H., Gasser, S., Gowen, B. G., Deng, W. and Jung, H. (2013). Regulation of ligands for the NKG2D activating receptor. Annu Rev Immunol 31: 413-441.
  5. Tang, M.L.F., and Gasser, S. (2013). ATM activation mediates anticancer immunosurveillance by natural killer and T cells. OncoImmunology 2: e24438.
  6. Ho, S. S. and Gasser, S. (2013). NKG2D ligands link oncogenic RAS to innate immunity. Oncoimmunology 2(1): e22244.
  7. Ge, M. Q., Ho, A. W., Tang, Y., Wong, K. H., Chua, B. Y., Gasser, S. and Kemeny, D. M. (2012). NK cells regulate CD8+ T cell priming and dendritic cell migration during influenza A infection by IFN-gamma and perforin-dependent mechanisms. J Immunol 189(5): 2099-2109.
  8. Liu, X. V., Ho, S. S., Tan, J. J., Kamran, N. and Gasser, S. (2012). Ras activation induces expression of Raet1 family NK receptor ligands. J Immunol 189(4): 1826-1834.
  9. Yeo, Y. A., Martinez Gomez, J. M., Croxford, J. L., Gasser, S., Ling, E. A. and Schwarz, H. (2012). CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species. J Neuroinflammation 9: 173.
  10. Xiong, G.M., and Gasser, S. (2011). Integration of the DNA Damage Response with Innate Immune Pathways. Intech: 715-737.
  11. Croxford, J. L. and Gasser, S. (2011). Damage control: how HIV survives the editor APOBEC3G. Nat Immunol 12(10): 925-927.
  12. Fine, J. H., Chen, P., Mesci, A., Allan, D. S., Gasser, S., Raulet, D. H. and Carlyle, J. R. (2010). Chemotherapy-induced genotoxic stress promotes sensitivity to natural killer cell cytotoxicity by enabling missing-self recognition. Cancer Res 70(18): 7102-7113.
  13. Lee, S. K. and Gasser, S. (2010). The role of natural killer cells in cancer therapy. Front Biosci (Elite Ed) 2: 380-391.
  14. Gasser, S. (2007). DNA damage response and development of targeted cancer treatments. Ann Med 39(6): 457-464.
  15. Gasser, S. and Raulet, D. H. (2006). Activation and self-tolerance of natural killer cells. Immunol Rev 214: 130-142..
  16. Gasser, S. and Raulet, D. (2006). The DNA damage response, immunity and cancer. Semin Cancer Biol 16(5): 344-347.
  17. Bianchi, T., Gasser, S., Trumpp, A. and MacDonald, H. R. (2006). c-Myc acts downstream of IL-15 in the regulation of memory CD8 T-cell homeostasis. Blood 107(10): 3992-3999.
  18. Gasser, S. and Raulet, D. H. (2006). The DNA damage response arouses the immune system. Cancer Res 66(8): 3959-3962.
  19. Gasser, S., Orsulic, S., Brown, E. J. and Raulet, D. H. (2005). The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature 436(7054): 1186-1190.