Education
Clinical Biochemist, Universidad de la República, Uruguay, 2007
Current position
Technical Assistant, Laboratory of Molecular & Structural Microbiology, Institut Pasteur de Montevideo, Uruguay
Publications
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San Martin, F., Mechaly, A. E., Larrieux, N., Wunder, E. A., Jr., Ko, A. I., Picardeau, M., Trajtenberg, F. and Buschiazzo, A. (2017). Crystallization of FcpA from Leptospira, a novel flagellar protein that is essential for pathogenesis. Acta Crystallogr F Struct Biol Commun 73(Pt 3): 123-129.
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Trajtenberg, F., Imelio, J. A., Machado, M. R., Larrieux, N., Marti, M. A., Obal, G., Mechaly, A. E. and Buschiazzo, A. (2016). Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action. Elife 5.
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Moran-Barrio, J., Lisa, M. N., Larrieux, N., Drusin, S. I., Viale, A. M., Moreno, D. M., Buschiazzo, A. and Vila, A. J. (2016). Crystal Structure of the Metallo-beta-Lactamase GOB in the Periplasmic Dizinc Form Reveals an Unusual Metal Site. Antimicrob Agents Chemother 60(10): 6013-6022.
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Obal, G., Trajtenberg, F., Carrion, F., Tome, L., Larrieux, N., Zhang, X., Pritsch, O. and Buschiazzo, A. (2015). STRUCTURAL VIROLOGY. Conformational plasticity of a native retroviral capsid revealed by x-ray crystallography. Science 349(6243): 95-98.
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Trajtenberg, F., Albanesi, D., Ruétalo, N., Botti, H., Mechaly, A. E., Nieves, M., Aguilar, P. S., Cybulski, L., Larrieux, N., de Mendoza, D. and Buschiazzo, A. (2014). Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation. MBio 5(6): e02105.
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Trajtenberg, F., Altabe, S., Larrieux, N., Ficarra, F., de Mendoza, D., Buschiazzo, A. and Schujman, G. E. (2014). Structural insights into bacterial resistance to cerulenin. FEBS J 281(10): 2324-2338.
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Martinez, A., Peluffo, G., Petruk, A. A., Hugo, M., Pineyro, D., Demicheli, V., Moreno, D. M., Lima, A., Batthyany, C., Duran, R., Robello, C., Marti, M. A., Larrieux, N., Buschiazzo, A., Trujillo, M., Radi, R. and Piacenza, L. (2014). Structural and molecular basis of the peroxynitrite-mediated nitration and inactivation of Trypanosoma cruzi iron-superoxide dismutases (Fe-SODs) A and B: disparate susceptibilities due to the repair of Tyr35 radical by Cys83 in Fe-SODB through intramolecular electron transfer. J Biol Chem 289(18): 12760-12778.
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Buschiazzo, A., Muia, R., Larrieux, N., Pitcovsky, T., Mucci, J. and Campetella, O. (2012). Trypanosoma cruzi trans-sialidase in complex with a neutralizing antibody: structure/function studies towards the rational design of inhibitors. PLoS Pathog 8(1): e1002474.
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Ortiz, C., Larrieux, N., Medeiros, A., Botti, H., Comini, M. and Buschiazzo, A. (2011). Expression, crystallization and preliminary X-ray crystallographic analysis of glucose-6-phosphate dehydrogenase from the human pathogen Trypanosoma cruzi in complex with substrate. Acta Crystallogr Sect F Struct Biol Cryst Commun 67(Pt 11): 1457-1461.