Education

Ph.D. in Molecular and Cell Biology, Nanyang Technological University (NTU), Singapore, 2006

Current position

Research Fellow, School of Biological Sciences, NTU, Singapore (2010-present)

Publications

1. Liao, Y., Fung, T. S., Huang, M., Fang, S. G., Zhong, Y. and Liu, D. X. (2013). Upregulation of CHOP/GADD153 during coronavirus infectious bronchitis virus infection modulates apoptosis by restricting activation of the extracellular signal-regulated kinase pathway. J Virol 87(14): 8124-8134.
   
2. Zhong, Y., Liao, Y., Fang, S., Tam, J. P. and Liu, D. X. (2012). Up-regulation of Mcl-1 and Bak by coronavirus infection of human, avian and animal cells modulates apoptosis and viral replication. PLoS One 7(1): e30191.
   
3. Liao, Y., Wang, X., Huang, M., Tam, J. P. and Liu, D. X. (2011). Regulation of the p38 mitogen-activated protein kinase and dual-specificity phosphatase 1 feedback loop modulates the induction of interleukin 6 and 8 in cells infected with coronavirus infectious bronchitis virus. Virology 420(2): 106-116.
   
4. Wang, X.*, Liao, Y.*, Yap, P. L., Png, K. J., Tam, J. P. and Liu, D. X. (2009). Inhibition of protein kinase R activation and upregulation of GADD34 expression play a synergistic role in facilitating coronavirus replication by maintaining de novo protein synthesis in virus-infected cells. J Virol 83(23): 12462-12472. (*Co-first author)
   
5. Liu, D. X., Yuan, Q. and Liao, Y. (2007). Coronavirus envelope protein: a small membrane protein with multiple functions. Cell Mol Life Sci 64(16): 2043-2048.
   
6. Yuan, Q., Liao, Y., Torres, J., Tam, J. P. and Liu, D. X. (2006). Biochemical evidence for the presence of mixed membrane topologies of the severe acute respiratory syndrome coronavirus envelope protein expressed in mammalian cells. FEBS Lett 580(13): 3192-3200.
   
7. Liao, Y., Yuan, Q., Torres, J., Tam, J. P. and Liu, D. X. (2006). Biochemical and functional characterization of the membrane association and membrane permeabilizing activity of the severe acute respiratory syndrome coronavirus envelope protein. Virology 349(2): 264-275.
   
8. Liao, Y., Tam, J. P. and Liu, D. X. (2006). Viroporin activity of SARS-CoV E protein. Adv Exp Med Biol 581: 199-202.
   
9. Wang, X. X., Liao, Y., Wong, S. M. and Liu, D. X. (2006). Identification and characterization of a unique ribosomal frameshifting signal in SARS-CoV ORF3a. Adv Exp Med Biol 581: 89-92.
10. Liao, Y., Lescar, J., Tam, J. P. and Liu, D. X. (2004). Expression of SARS-coronavirus envelope protein in Escherichia coli cells alters membrane permeability. Biochem Biophys Res Commun 325(1): 374-380.