John Beatty Department of Microbiology and Immunology, University of British Columbia, Canada
5 protocols

Paul Fogg Department of Microbiology and Immunology, University of British Columbia, Canada
1 protocol
Andrea Puhar MIMS and Department of Molecular Biology, Umeå University
52 protocols

Esteban Paredes-Osses Institute of Public Health
7 protocols

Maria Sinetova Laboratory of Intracellular Regulation, Institute of Plant Physiology, Russian Academy of Sciences, Russia
45 protocols

Migla Miskinyte Instituto Gulbenkian de Ciencia
11 protocols

Alexander B Westbye
  • Post-Doc, NIOZ Royal Netherlands Institute for Sea Research
Research focus
  • Microbiology
  • Prokaryotic physiology, genetics and gene flow
  • 1 Author merit


PhD, The University of British Columbia, 2016


Guaranteeing a captive audience: coordinated regulation of gene transfer agent (GTA) production and recipient capability by cellular regulators.
Westbye AB, Beatty JT, Lang AS.
Curr Opin Microbiol. 2017 Jun 6;38:122-129. doi: 10.1016/j.mib.2017.05.003.

The Distribution, Evolution, and Roles of Gene Transfer Agents in Prokaryotic Genetic Exchange.
Lang AS, Westbye AB, Beatty JT.
Annu Rev Virol. 2017 Sep 29;4(1):87-104. doi: 10.1146/annurev-virology-101416-041624.

The Rhodobacter capsulatus gene transfer agent is induced by nutrient depletion and the RNAP omega subunit.
Westbye AB, O'Neill Z, Schellenberg-Beaver T, Beatty JT.
Microbiology. 2017 Sep;163(9):1355-1363. doi: 10.1099/mic.0.000519

The SOS Response Master Regulator LexA Regulates the Gene Transfer Agent of Rhodobacter capsulatus and Represses Transcription of the Signal Transduction Protein CckA.
Kuchinski KS, Brimacombe CA, Westbye AB, Ding H, Beatty JT.
J Bacteriol. 2016 Feb 1;198(7):1137-48. doi: 10.1128/JB.00839-15.

The Gene Transfer Agent RcGTA Contains Head Spikes Needed for Binding to the Rhodobacter capsulatus Polysaccharide Cell Capsule.
Westbye AB, Kuchinski K, Yip CK, Beatty JT.
J Mol Biol. 2016 Jan 29;428(2 Pt B):477-91. doi: 10.1016/j.jmb.2015.12.010.

Gene co-expression network analysis in Rhodobacter capsulatus and application to comparative expression analysis of Rhodobacter sphaeroides.
Peña-Castillo L, Mercer RG, Gurinovich A, Callister SJ, Wright AT, Westbye AB, Beatty JT, Lang AS.
BMC Genomics. 2014 Aug 28;15:730. doi: 10.1186/1471-2164-15-730.

Phosphate concentration and the putative sensor kinase protein CckA modulate cell lysis and release of the Rhodobacter capsulatus gene transfer agent.
Westbye AB, Leung MM, Florizone SM, Taylor TA, Johnson JA, Fogg PC, Beatty JT.
J Bacteriol. 2013 Nov;195(22):5025-40. doi: 10.1128/JB.00669-13.

One for all or all for one: heterogeneous expression and host cell lysis are key to gene transfer agent activity in Rhodobacter capsulatus.
Fogg PC, Westbye AB, Beatty JT.
PLoS One. 2012;7(8):e43772. doi: 10.1371/journal.pone.0043772.
1 Protocol published
Endolysin Expression, Purification and Activity Determination by Zymography
Authors:  Alexander B. Westbye, Paul C. Fogg and John Thomas Beatty, date: 08/20/2014, view: 12877, Q&A: 0
Endolysins are peptidoglycan-degrading (muralytic) enzymes produced by many bacteriophages for cell lysis of the host bacterium. The enzymatic activity of muralytic enzymes can be assayed qualitatively using a zymogram containing incorporated ...
6 Protocols reviewed
Quantification of Bacterial Twitching Motility in Dense Colonies Using Transmitted Light Microscopy and Computational Image Analysis
Authors:  Benjamin Smith, Jianfang Li, Matteo Metruccio, Stephanie Wan, David Evans and Suzanne Fleiszig, date: 04/20/2018, view: 4965, Q&A: 0
A method was developed to allow the quantification and mapping of relative bacterial twitching motility in dense samples, where tracking of individual bacteria was not feasible. In this approach, movies of bacterial films were acquired using ...
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Adhesion and Invasion Assay Procedure Using Caco-2 Cells for Listeria monocytogenes
Authors:  Swetha Reddy and Frank Austin, date: 05/05/2017, view: 11728, Q&A: 0
Listeria monocytogenes is an important Gram-positive foodborne pathogen that is a particular problem in ready-to-eat food. It has an ability to survive in harsh conditions like refrigeration temperatures and high salt concentrations and is ...
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