Runsheng Chen
  • Institute of Biophysics, Chinese Academy of Sciences
Research focus
  • Neuroscience
  • 1 Author merit


Bachelor, University of Science and Technology of China, China, 1964

Current position

Professor, Key Laboratory of RNA Biology, Institute of Biophysics, CAS, China


  1. Chen, X., Hao, Y., Cui, Y., Fan, Z., He, S., Luo, J. and Chen, R. (2017). LncVar: a database of genetic variation associated with long non-coding genes. Bioinformatics 33(1): 112-118.
  2. Zhao, Y., Li, H., Fang, S., Kang, Y., Wu, W., Hao, Y., Li, Z., Bu, D., Sun, N., Zhang, M. Q. and Chen, R. (2016). NONCODE 2016: an informative and valuable data source of long non-coding RNAs. Nucleic Acids Res 44(D1): D203-208.
  3. Liu, L., Yue, H., Liu, Q., Yuan, J., Li, J., Wei, G., Chen, X., Lu, Y., Guo, M., Luo, J. and Chen, R. (2016). LncRNA MT1JP functions as a tumor suppressor by interacting with TIAR to modulate the p53 pathway. Oncotarget 7(13): 15787-15800.
  4. Cui, Y., Chen, X., Luo, H., Fan, Z., Luo, J., He, S., Yue, H., Zhang, P. and Chen, R. (2016). BioCircos.js: an interactive Circos JavaScript library for biological data visualization on web applications. Bioinformatics 32(11): 1740-1742.
  5. Xiao, T., Liu, L., Li, H., Sun, Y., Luo, H., Li, T., Wang, S., Dalton, S., Zhao, R. C. and Chen, R. (2015). Long Noncoding RNA ADINR Regulates Adipogenesis by Transcriptionally Activating C/EBPalpha. Stem Cell Reports 5(5): 856-865.
  6. Wang, Y., He, L., Du, Y., Zhu, P., Huang, G., Luo, J., Yan, X., Ye, B., Li, C., Xia, P., Zhang, G., Tian, Y., Chen, R. and Fan, Z. (2015). The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling. Cell Stem Cell 16(4): 413-425.
  7. Yuan, J., Wu, W., Xie, C., Zhao, G., Zhao, Y. and Chen, R. (2014). NPInter v2.0: an updated database of ncRNA interactions. Nucleic Acids Res 42(Database issue): D104-108.
  8. Li, J., Chen, Z., Tian, L., Zhou, C., He, M. Y., Gao, Y., Wang, S., Zhou, F., Shi, S., Feng, X., Sun, N., Liu, Z., Skogerboe, G., Dong, J., Yao, R., Zhao, Y., Sun, J., Zhang, B., Yu, Y., Shi, X., Luo, M., Shao, K., Li, N., Qiu, B., Tan, F., Chen, R. and He, J. (2014). LncRNA profile study reveals a three-lncRNA signature associated with the survival of patients with oesophageal squamous cell carcinoma. Gut 63(11): 1700-1710.
  9. Lu, X., Wang, L., Chen, S., He, L., Yang, X., Shi, Y., Cheng, J., Zhang, L., Gu, C. C., Huang, J., Wu, T., Ma, Y., Li, J., Cao, J., Chen, J., Ge, D., Fan, Z., Li, Y., Zhao, L., Li, H., Zhou, X., Chen, L., Liu, D., Chen, J., Duan, X., Hao, Y., Wang, L., Lu, F., Liu, Z., Yao, C., Shen, C., Pu, X., Yu, L., Fang, X., Xu, L., Mu, J., Wu, X., Zheng, R., Wu, N., Zhao, Q., Li, Y., Liu, X., Wang, M., Yu, D., Hu, D., Ji, X., Guo, D., Sun, D., Wang, Q., Yang, Y., Liu, F., Mao, Q., Liang, X., Ji, J., Chen, P., Mo, X., Li, D., Chai, G., Tang, Y., Li, X., Du, Z., Liu, X., Dou, C., Yang, Z., Meng, Q., Wang, D., Wang, R., Yang, J., Schunkert, H., Samani, N. J., Kathiresan, S., Reilly, M. P., Erdmann, J., Coronary, A. D. G.-W. R., Meta-Analysis, C., Peng, X., Wu, X., Liu, D., Yang, Y., Chen, R., Qiang, B. and Gu, D. (2012). Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat Genet 44(8): 890-894.
  10. Wang, Y., Chen, J., Wei, G., He, H., Zhu, X., Xiao, T., Yuan, J., Dong, B., He, S., Skogerbo, G. and Chen, R. (2011). The Caenorhabditis elegans intermediate-size transcriptome shows high degree of stage-specific expression. Nucleic Acids Res 39(12): 5203-5214.
  11. Zhao, Y., He, S., Liu, C., Ru, S., Zha, H., Yang, Z., Yang, P., Yuan, X., Sun, S., Bu, D., Huang, J., Skogerbø, G. and Chen, R. (2008). MicroRNA regulation of messenger-like noncoding RNAs: a network of mutual microRNA control. Trends in Genetics 24: 323-327.
  12. He, S., Su, H., Liu, C., Skogerbo, G., He, H., He, D., Zhu, X., Liu, T., Zhao, Y. and Chen, R. (2008). MicroRNA-encoding long non-coding RNAs. BMC Genomics 9: 236.
  13. Aftab, M. N., He, H., Skogerbo, G. and Chen, R. (2008). Microarray analysis of ncRNA expression patterns in Caenorhabditis elegans after RNAi against snoRNA associated proteins. BMC Genomics 9: 278.
  14. He, H., Wang, J., Liu, T., Liu, X. S., Li, T., Wang, Y., Qian, Z., Zheng, H., Zhu, X., Wu, T., Shi, B., Deng, W., Zhou, W., Skogerbo, G. and Chen, R. (2007). Mapping the C. elegans noncoding transcriptome with a whole-genome tiling microarray. Genome Res 17(10): 1471-1477.
  15. Zhang, Z., Liu, C., Skogerbo, G., Zhu, X., Lu, H., Chen, L., Shi, B., Zhang, Y., Wang, J., Wu, T. and Chen, R. (2006). Dynamic changes in subgraph preference profiles of crucial transcription factors. PLoS Comput Biol 2(5): e47.
  16. Zhang, Y., Li, S., Skogerbo, G., Zhang, Z., Zhu, X., Zhang, Z., Sun, S., Lu, H., Shi, B. and Chen, R. (2006). Phylophenetic properties of metabolic pathway topologies as revealed by global analysis. BMC Bioinformatics 7: 252.
  17. Muzny, D. M., Scherer, S. E., Kaul, R., Wang, J., Yu, J., Sudbrak, R., Buhay, C. J., Chen, R., Cree, A., Ding, Y., Dugan-Rocha, S., Gill, R., Gunaratne, P., Harris, R. A., Hawes, A. C., Hernandez, J., Hodgson, A. V., Hume, J., Jackson, A., Khan, Z. M., Kovar-Smith, C., Lewis, L. R., Lozado, R. J., Metzker, M. L., Milosavljevic, A., Miner, G. R., Morgan, M. B., Nazareth, L. V., Scott, G., Sodergren, E., Song, X. Z., Steffen, D., Wei, S., Wheeler, D. A., Wright, M. W., Worley, K. C., Yuan, Y., Zhang, Z., Adams, C. Q., Ansari-Lari, M. A., Ayele, M., Brown, M. J., Chen, G., Chen, Z., Clendenning, J., Clerc-Blankenburg, K. P., Chen, R., Chen, Z., Davis, C., Delgado, O., Dinh, H. H., Dong, W., Draper, H., Ernst, S., Fu, G., Gonzalez-Garay, M. L., Garcia, D. K., Gillett, W., Gu, J., Hao, B., Haugen, E., Havlak, P., He, X., Hennig, S., Hu, S., Huang, W., Jackson, L. R., Jacob, L. S., Kelly, S. H., Kube, M., Levy, R., Li, Z., Liu, B., Liu, J., Liu, W., Lu, J., Maheshwari, M., Nguyen, B. V., Okwuonu, G. O., Palmeiri, A., Pasternak, S., Perez, L. M., Phelps, K. A., Plopper, F. J., Qiang, B., Raymond, C., Rodriguez, R., Saenphimmachak, C., Santibanez, J., Shen, H., Shen, Y., Subramanian, S., Tabor, P. E., Verduzco, D., Waldron, L., Wang, J., Wang, J., Wang, Q., Williams, G. A., Wong, G. K., Yao, Z., Zhang, J., Zhang, X., Zhao, G., Zhou, J., Zhou, Y., Nelson, D., Lehrach, H., Reinhardt, R., Naylor, S. L., Yang, H., Olson, M., Weinstock, G. and Gibbs, R. A. (2006). The DNA sequence, annotation and analysis of human chromosome 3. Nature 440(7088): 1194-1198.
  18. He, H., Cai, L., Skogerbo, G., Deng, W., Liu, T., Zhu, X., Wang, Y., Jia, D., Zhang, Z., Tao, Y., Zeng, H., Aftab, M. N., Cui, Y., Liu, G. and Chen, R. (2006). Profiling Caenorhabditis elegans non-coding RNA expression with a combined microarray. Nucleic Acids Res 34(10): 2976-2983.
  19. Deng, W., Zhu, X., Skogerbo, G., Zhao, Y., Fu, Z., Wang, Y., He, H., Cai, L., Sun, H., Liu, C., Li, B., Bai, B., Wang, J., Jia, D., Sun, S., He, H., Cui, Y., Wang, Y., Bu, D. and Chen, R. (2006). Organization of the Caenorhabditis elegans small non-coding transcriptome: genomic features, biogenesis, and expression. Genome Res 16(1): 20-29.
  20. Liu, C., Bai, B., Skogerbo, G., Cai, L., Deng, W., Zhang, Y., Bu, D., Zhao, Y. and Chen, R. (2005). NONCODE: an integrated knowledge database of non-coding RNAs. Nucleic Acids Res 33(Database issue): D112-115.
  21. Yu, J., Hu, S., Wang, J., Wong, G. K., Li, S., Liu, B., Deng, Y., Dai, L., Zhou, Y., Zhang, X., Cao, M., Liu, J., Sun, J., Tang, J., Chen, Y., Huang, X., Lin, W., Ye, C., Tong, W., Cong, L., Geng, J., Han, Y., Li, L., Li, W., Hu, G., Huang, X., Li, W., Li, J., Liu, Z., Li, L., Liu, J., Qi, Q., Liu, J., Li, L., Li, T., Wang, X., Lu, H., Wu, T., Zhu, M., Ni, P., Han, H., Dong, W., Ren, X., Feng, X., Cui, P., Li, X., Wang, H., Xu, X., Zhai, W., Xu, Z., Zhang, J., He, S., Zhang, J., Xu, J., Zhang, K., Zheng, X., Dong, J., Zeng, W., Tao, L., Ye, J., Tan, J., Ren, X., Chen, X., He, J., Liu, D., Tian, W., Tian, C., Xia, H., Bao, Q., Li, G., Gao, H., Cao, T., Wang, J., Zhao, W., Li, P., Chen, W., Wang, X., Zhang, Y., Hu, J., Wang, J., Liu, S., Yang, J., Zhang, G., Xiong, Y., Li, Z., Mao, L., Zhou, C., Zhu, Z., Chen, R., Hao, B., Zheng, W., Chen, S., Guo, W., Li, G., Liu, S., Tao, M., Wang, J., Zhu, L., Yuan, L. and Yang, H. (2002). A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science 296(5565): 79-92.
  22. Bu, D., Zhao, Y., Cai, L., Xue, H., Zhu, X., Lu, H., Zhang, J., Sun, S., Ling, L., Zhang, N., Li, G. and Chen, R. (2003). Topological structure analysis of the protein-protein interaction network in budding yeast. Nucleic Acids Res 31(9): 2443-2450.
  23. Bao, Q., Tian, Y., Li, W., Xu, Z., Xuan, Z., Hu, S., Dong, W., Yang, J., Chen, Y., Xue, Y., Xu, Y., Lai, X., Huang, L., Dong, X., Ma, Y., Ling, L., Tan, H., Chen, R., Wang, J., Yu, J. and Yang, H. (2002). A complete sequence of the T. tengcongensis genome. Genome Res 12(5): 689-700.
  24. Li, W., Fang, W., Ling, L., Wang, J., Xuan, Z. and Chen, R. (2002). Phylogeny Based on Whole Genome as inferred from Complete Information Set Analysis. J Biol Phys 28(3): 439-447.
1 Protocol published
Proboscis Extension Reflex in Apis mellifera [Honeybee] with Only One Antenna
Authors:  Yu Guo, Zilong Wang, Zhijiang Zeng, Shaowu Zhang and Runsheng Chen, date: 12/05/2017, view: 5056, Q&A: 0
The proboscis extension reflex (PER) is a common classical conditioned reflex which is widely used in the neurology and ethology. In honeybees, PER experiments can train bees to associate an odor with a reward or punishment. Here we present a ...
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