Prashanth Suravajhala
  • Research scientist, Birla Institute of Scientific Research
Research focus
  • Systems biology
  • Long Non-coding RNA - Protein interactions, Systems Genomics and Biology of rare genetic disorders, Next Generation Sequencng
1 Protocol feedback
Gene Networks Based on the Graphical Gaussian Model
Author:  Shisong Ma, date: 02/20/2012, view: 8875, Q&A: 1
This protocol describes how to build a gene network based on the graphical Gaussian model (GGM) from large scale microarray data. GGM uses partial correlation coefficient (pcor) to infer co-expression relationship between genes. Compared to the traditional Pearson’ correlation coefficient, partial correlation is a better measurement of direct ...