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Jerry Shay Department of Cell Biology, University of Texas Southwestern Medical Center, USA
3 protocols
Amriti Lulla UT MD Anderson Cancer Center
3 protocols

Ana Santos Almeida University College Cork
4 protocols

Jia Li SRI International
50 protocols

Ralph Boettcher Max Planck Institute for Biochemistry
33 protocols

Reviewer
ilgen Mender
  • Post-Doc, University of Texas Southwestern Medical Center
Research focus
  • Cancer biology
  • Telomeres, telomerase, telomerase inhibitors, drug resistance, 6-thio-dG, non-small lung cancer
  • 3 Author merit

Education

PhD, Hacettepe University, 2014

Lab information

Jerry Shay Lab
http://www.utsouthwestern.edu/labs/shay-wright/

Publications

3 Protocols published
Telomere Restriction Fragment (TRF) Analysis
Authors:  Ilgen Mender and Jerry W. Shay, date: 11/20/2015, view: 9866, Q&A: 0
While telomerase is expressed in ~90% of primary human tumors, most somatic tissue cells except transiently proliferating stem-like cells do not have detectable telomerase activity (Shay and Wright, 1996; Shay and Wright, 2001). Telomeres ...
Telomerase Repeated Amplification Protocol (TRAP)
Authors:  Ilgen Mender and Jerry W. Shay, date: 11/20/2015, view: 8698, Q&A: 1
Telomeres are found at the end of eukaryotic linear chromosomes, and proteins that bind to telomeres protect DNA from being recognized as double-strand breaks thus preventing end-to-end fusions (Griffith et al., 1999). However, due to the ...
2 Protocols reviewed
GFP-Grb2 Translocation Assay Using High-content Imaging to Screen for Modulators of EGFR-signaling
Authors:  Julia Petschnigg and Robin Ketteler, date: 09/05/2017, view: 2281, Q&A: 0
High-content screening is a useful tool to understand complex cellular processes and to identify genes, proteins or small molecule compounds that modulate such pathways. High-content assays monitor the function of a protein or pathway by visualizing ...
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Intracaecal Orthotopic Colorectal Cancer Xenograft Mouse Model
Authors:  Hsin-Wei Liao and Mien-Chie Hung, date: 06/05/2017, view: 4103, Q&A: 1
The host microenvironment plays a prominent role in tumor growth, angiogenesis, invasion, metastasis, and response to therapy. Orthotopic tumor model mimics the natural environment of tumor development and provides an effective approach to ...
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