Stewart Loh Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse
1 protocol

Darren Carpizo University of Rochester School of Medicine and Dentistry Rochester
1 protocol

Jeung- Ha Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse
1 protocol

Xin Yu
  • Rutgers Cancer Institute of New Jersey New Brunswick
  • 1 Author merit
1 Protocol published
Urea Denaturation, Zinc Binding, and DNA Binding Assays of Mutant p53 DNA-binding Domains and Full-length Proteins
Authors:  Jeung-Hoi Ha, Xin Yu, Darren R. Carpizo and Stewart N. Loh, date: 10/20/2021, view: 370, Q&A: 0

In the cell, the thermodynamic stability of a protein – and hence its biological activity – can change dramatically as a result of perturbations in its amino acid sequence and the concentration of stabilizing ligands. This interplay is

...
We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.