Kavita A Iyer
  • Post-Doc, Virginia Commonwealth University
Research focus
  • Biophysics
  • Ryanodine receptors
  • 0 Author merit

Education

PhD, Virginia Commonwealth University, 2016

Lab information

Montserrat Samso's Lab

Publications

1. Iyer, K. A.; Hu, Y.; Nayak, A. R.; Kurebayashi, N.; Murayama, T.; Samsó, M. Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci. Adv. 2020, 6, eabb2964.

2. Abdelkhalek, A.; Musayev, F. N.; Iyer, K. A.; Hemanth, P.; Safo, M.; Dukat, M. X-ray crystal structure of a 2-amino-3,4-dihydroquinazoline 5-HT3 serotonin receptor antagonist and related analogs. J. Mol. Struct. 2020, 1202, 127276.

3. Iyer, K. A.; Alix, K.; Eltit, J. M.; Solis Jr., E.; Pan, X.; Argade, M. D.; Khatri, S.; De Felice, L. J.; Sweet, D. H.; Schulte, M. K.; Dukat, M. Multi-modal antidepressant-like action of 6- and 7-chloro-2-aminodihydroquinazolines in the mouse tail suspension test. Psychopharmacology 2019, 236, 2093-2104.

4. Pan, X.; Iyer, K. A.; Liu, H.; Sweet, D. H.; Dukat, M. A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3). Bioorganic & Medicinal Chemistry Letters 2017, 27, 4440-4445.

5. Sguazzini, E.; Schmidt, H.; Iyer, K. A.; Kruse, A.; Dukat, M. Reevaluation of fenpropimorph as a σ receptor ligand: Structure-affinity relationship studies at human σ1 receptors. Bioorg. Med. Chem. Lett. 2017, 27, 2912-2919.
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