Nicola Harris Monash University AMREP campus Melbourne
1 protocol

tiffany bouchery immunology and pathology Monash University AMREP campus
1 protocol

Gillian Coakley
  • Postdoctoral researcher, immunology and pathology Monash University AMREP campus
Research focus
  • Immunology
  • 1 Author merit


PhD, The University of Edinburgh, 2016


References (2014 to now)
• Coakley G, Harris NL. The Intestinal Epithelium at the Forefront of Host-Helminth Interactions. Trends Parasitol. 2020;36(9):761-72.
• Drurey C, Coakley G, Maizels RM. Extracellular vesicles: new targets for vaccines against helminth parasites. Int J Parasitol. 2020;50(9):623-33.
• Coakley G, Volpe B, Bouchery T, Shah K, Butler A, Geldhof P, et al. Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae. Parasite Immunol. 2020;42(7):e12728.
• Coakley G, Harris NL. Interactions between macrophages and helminths. Parasite Immunol. 2020;42(7):e12717.
• Bouchery T, Moyat M, Sotillo J, Silverstein S, Volpe B, Coakley G, et al. Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps. Cell Host Microbe. 2020;27(2):277-89 e6.
• Moyat M, Coakley G, Harris N. Stromal-Immune Cell Crosstalk Maintains Type 2 Immune Cell Populations within Visceral Adipose Tissue. Immunometabolism. 2020;2(3):e200018.
• Coakley G, Harris NL. Helminths and microbiota - partners in arthritis prevention? Nat Rev Rheumatol. 2019;15(8):454-5.
• Coakley G, Wright MD, Borger JG. Schistosoma mansoni-Derived Lipids in Extracellular Vesicles: Potential Agonists for Eosinophillic Tissue Repair. Front Immunol. 2019;10:1010.
• Moyat M, Coakley G, Harris NL. The interplay of type 2 immunity, helminth infection and the microbiota in regulating metabolism. Clin Transl Immunology. 2019;8(11):e01089.
• Ramirez MI, Amorim MG, Gadelha C, Milic I, Welsh JA, Freitas VM, et al. Technical challenges of working with extracellular vesicles. Nanoscale. 2018;10(3):881-906.
• Coakley G, McCaskill JL, Borger JG, Simbari F, Robertson E, Millar M, et al. Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity. Cell Rep. 2017;19(8):1545-57.
• Coakley G, Buck AH, Maizels RM. Host parasite communications-Messages from helminths for the immune system: Parasite communication and cell-cell interactions. Mol Biochem Parasitol. 2016;208(1):33-40.
• Simbari F, McCaskill J, Coakley G, Millar M, Maizels RM, Fabrias G, et al. Plasmalogen enrichment in exosomes secreted by a nematode parasite versus those derived from its mouse host: implications for exosome stability and biology. J Extracell Vesicles. 2016;5:30741.
• Coakley G, Maizels RM, Buck AH. Exosomes and Other Extracellular Vesicles: The New Communicators in Parasite Infections. Trends Parasitol. 2015;31(10):477-89.
• Johnston CJ, Robertson E, Harcus Y, Grainger JR, Coakley G, Smyth DJ, et al. Cultivation of Heligmosomoides polygyrus: an immunomodulatory nematode parasite and its secreted products. J Vis Exp. 2015(98):e52412.
• Buck AH, Coakley G, Simbari F, McSorley HJ, Quintana JF, Le Bihan T, et al. Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Nat Commun. 2014;5:5488.
1 Protocol published
Preparation of Nippostrongylus brasiliensis Larvae for the Study of Host Skin Response
Authors:  Tiffany Bouchery, Gillian Coakley and Nicola L. Harris, date: 12/20/2020, view: 747, Q&A: 0

Hookworms are skin penetrating parasites, however in the laboratory the hookworm model Nippostrongylus brasiliensis, the parasite is traditionally administered subcutaneously bypassing the skin (epidermis and dermis). Here, we describe two

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