Deborah Hinton Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, NIDDK, National Institutes of Health, USA
2 protocols

Leslie Knipling National Institutes of Health Bethesda, MD
1 protocol

Alice Boulanger National Institutes of Health Bethesda
1 protocol

Meng-Lun Hsieh
  • National Institutes of Health Bethesda, MD
  • 1 Author merit
1 Protocol published
Combining Gel Retardation and Footprinting to Determine Protein-DNA Interactions of Specific and/or Less Stable Complexes
Authors:  Meng-Lun Hsieh, Alice Boulanger, Leslie G. Knipling and Deborah M. Hinton, date: 12/05/2020, view: 1250, Q&A: 0

DNA footprinting is a classic technique to investigate protein-DNA interactions. However, traditional footprinting protocols can be unsuccessful or difficult to interpret if the binding of the protein to the DNA is weak, the protein has a fast

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