Weihui Wu Department of Microbiology College of Life Sciences, Nankai University
1 protocol

Xiaolei Pan
  • Postdoctoral research Fellow, Department of Microbiology College of Life Sciences, Nankai University
Research focus
  • Microbiology
  • 1 Author merit


Ph.D., Nankai University, 2016


1. Xia Y, Weng Y, Xu C, Wang D, Pan X, Tian Z, Xia B, Li H, Chen R, Liu C, Jin Y, Bai F, Cheng Z, Kuipers OP, Wu W. Endoribonuclease YbeY Is Essential for RNA Processing and Virulence in Pseudomonas aeruginosa. (2020) mBio. 11(3):e00659-20.
2. Pan X, Fan Z, Chen L, Liu C, Bai F, Wei Y, Tian Z, Dong Y, Shi J, Chen H, Jin Y, Cheng Z, Jin S, Lin J, Wu W. PvrA is a novel regulator that contributes to Pseudomonas aeruginosa pathogenesis by controlling bacterial utilization of long chain fatty acids. (2020) Nucleic Acids Res. 48(11):5967-5985.
3. Xia Y, Wang D, Pan X, Xia B, Weng Y, Long Y, Ren H, Zhou J, Jin Y, Bai F, Cheng Z, Jin S, Wu W. TpiA is a Key Metabolic Enzyme That Affects Virulence and Resistance to Aminoglycoside Antibiotics through CrcZ in Pseudomonas aeruginosa. (2020) mBio. 11(1). pii: e02079-19.
4. Fan Z, Chen H, Li M, Pan X, Fu W, Ren H, Chen R, Bai F, Jin Y, Cheng Z, Jin S, Wu W. Pseudomonas aeruginosa Polynucleotide Phosphorylase Contributes to Ciprofloxacin Resistance by Regulating PrtR. (2019) Front Microbiol. Jul 30;10:1762.
5. Liu C, Pan X, Xia B, Chen F, Jin Y, Bai F, Priebe G, Cheng Z, Jin S, Wu W. Construction of a Protective Vaccine Against Lipopolysaccharide-Heterologous Pseudomonas aeruginosa Strains Based on Expression Profiling of Outer Membrane Proteins During Infection. (2018) Front Immunol. 9:1737.
6. Fan Z, Xu C, Pan X, Dong Y, Ren H, Jin Y, Bai F, Cheng Z, Jin S, Wu W. Mechanisms of RsaL mediated tolerance to ciprofloxacin and carbenicillin in Pseudomonas aeruginosa. (2018) Curr Genet. Jun 27. doi: 10.1007/s00294-018-0863-3.
7. Deng X, Li M, Pan X, Zheng R, Liu C, Chen F, Liu X, Cheng Z, Jin S, Wu W. Fis Regulates Type III Secretion System by Influencing the Transcription of exsA in Pseudomonas aeruginosa Strain PA14. (2017) Front Microbiol. 8:669
8. Pan X, Dong Y, Fan Z, Liu C, Xia B, Shi J, Bai F, Jin Y, Cheng Z, Jin S and Wu W. In vivo host environment alters Pseudomonas aeruginosa susceptibility to aminoglycoside antibiotics. (2017) Front. Cell. Infect. Microbiol. 14;7:83.
9. Weng Y, Chen F, Liu Y, Zhao Q, Chen R, Pan X, Liu C, Cheng Z, Jin S, Jin Y, Wu W. Pseudomonas aeruginosa Enolase Influences Bacterial Tolerance to Oxidative Stresses and Virulence. (2016) Front Microbiol. 15;7:1999.
10. Chen G, Zhao Q, Zhu F, Chen R, Jin Y, Liu C, Pan X, Jin S, Wu W, Cheng Z. Oligoribonuclease is required for the type III secretion system and pathogenesis of Pseudomonas aeruginosa. (2016) Microbiol Res. 188-189:90-6.
1 Protocol published
Murine Acute Pneumonia Model of Pseudomonas aeruginosa Lung Infection
Authors:  Xiaolei Pan and Weihui Wu, date: 11/05/2020, view: 997, Q&A: 0
Animal infection models play significant roles in studying bacterial pathogenic mechanisms, host pathogen interaction as well as evaluating drug and vaccine efficacies. We have been utilizing an acute pneumonia model to study bacterial colonization ...
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