Rui Martins Department of Electrical & Computer University of Macau
1 protocol

Chuxia Deng Facaulty of Health Sciences, University of Macau, Macau
3 protocols

Yanwei Jia Institute of Microelectronics University of Macau
1 protocol

Shuhong Yi 1 protocol

Pui-In Mak
  • Professor, State-Key Laboratory of Analog and Mixed-Signal VLSI/IME and FST-ECE University of Macau
Research focus
  • Lab on a Chip/microfluidics
  • 1 Author merit


PhD, PhD, 2006


Ren Shen, Yanwei Jia, Pui-In Mak, and Rui P. Martins “Clip-to-Release on Amplification (CRoA): a Novel DNA Amplification Enhancer on and off Microfluidics,” RSC Lab on a Chip, 2020, 20, pp. 1928-1938. Ka Meng Lei, Dongwan Ha, Yi-Qiao Song, Robert Westervelt, Rui Martins, Pui-In Mak, and Donhee Ham, “Portable NMR with Parallelism,” ACS Analytical Chemistry, 2020, 92, 2, 2112-2120. Jiao Zhai, Haoran Li, Ada Hang-Heng Wong, Cheng Dong, Shuhong Yi, Yanwei Jia, Pui-In Mak, Chuxia Deng, and Rui P. Martins “A Digital Microfluidic System with 3D Microstructures for Single-Cell Culture,” Microsystems & Nanoengineering (Nature Publishing Group), (2020) 6:6. Jiao Zhai, Shuhong Yi, Yanwei Jia, Pui-In Mak, Rui P. Martins, “Cell-based Drug Screening on Microfluidics,” Elsevier Trends in Analytical Chemistry, 117 (2019) 231-241. Mingzhong Li, Cheng Dong, Man-Kay Law, Yanwei Jia, Pui-In Mak and Rui P. Martins, “ Hydrodynamic-flow-enhanced rapid mixer for isothermal DNA hybridization kinetics analysis on digital microfluidics platform,” Elsevier Sensors and Actuators B: Chemical, vol. 287, pp. 390-397, May 2019. Liang Wan, Jie Gao, Tianlan Chen, Cheng Dong, Haoran Li, Yan-Zi Wen, Zhao-Rong Lun, Yanwei Jia, Pui-In Mak, and Rui P. Martins, “LampPort - a handheld digital microfluidic device for loop-mediated isothermal amplification (LAMP),” Springer Biomedical Microdevices, (2019) 21:9. Ada Hang-Heng Wong, Haoran Li, Yanwei Jia, Pui-In Mak, R. P. Martins, Yan Liu, Chi Man Vong, Hang Cheong Wong, Pak Kin Wong, Haitao Wang, Heng Sun, Chu-Xia Deng, “Drug Screening of Cancer Cell Lines and Human Primary Tumors Using Droplet Microfluidics,” Scientific Reports (Nature Publishing Group), Aug. 2017. Cheng Dong, Yanwei Jia, Jie Gao, Tianlan Chen, Pui-In Mak, Mang-I Vai, and R. P. Martins, “3D Microblade Structure for Precise and Parallel Droplet Splitting on Digital Microfluidic Chips,” RSC Lab on a Chip, 2017,17, 896-904. Ka-Meng Lei, Pui-In Mak, Man-Kay Law and R. P. Martins, “CMOS Biosensors for In Vitro Diagnosis - Transducing Mechanisms and Applications,” RSC Lab on a Chip, 2016, 16, 3664-3681. Tianlan Chen, Yanwei Jia, Cheng Dong, Jie Gao, Pui-In Mak, and R. P. Martins, “Sub-7-Second Genotyping of Single-Nucleotide Polymorphism by High-Resolution Melting Curve Analysis on a Thermal Digital Microfluidic Device,” RSC Lab on a Chip, 2016, 16, 743-752. Yanwei Jia, Pui-In Mak, Conner Massey, Rui P. Martins and Lawrence J. Wangh, “Construction of a Microfluidic Chip for LATE-PCR Amplification and Detection of Single-Stranded DNA using Dried-Down Reagents,” RSC Lab on a Chip, 2013, 13, 4635–4641. Jie Gao, Xianming Liu, Tianlan Chen, Pui-In Mak, Yuguang Du, Mang-I Vai, Bingcheng Lin and Rui P. Martins, “An Intelligent Digital Microfluidic System with Fuzzy-Enhanced Feedback for Multi-Droplet Manipulation,” RSC Lab on a Chip, 2013, 13, 443-451.
1 Protocol published
A Novel and Robust Single-cell Trapping Method on Digital Microfluidics
Due to cell heterogeneity, the differences among individual cells are averaged out in bulk analysis methods, especially in the analysis of primary tumor biopsy samples from patients. To deeply understand the cell-to-cell variation in a primary ...
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