Riccardo Filadi University of Padova Padova
1 protocol

Federica Chiara University of Padova Padova
1 protocol

Francesco Ciscato University of Padova Padova
1 protocol

Andrea Rasola
  • Faculty, University of Padova Padova
Research focus
  • Cancer biology
  • 1. Changes in mitochondrial energy metabolism during neoplastic transformation, with a particular focus on tumors caused by the genetic syndrome neurofibromatosis type I.
    2. Analysis of the role played by the mitochondrial chaperone TRAP1 in the tumorigenic process.
    3. Mitochondrial kinases in survival and metabolic rewiring of tumor cells.
    4. Study of the regulatory mechanisms and of the apoptotic role of the mitochondrial permeability transition pore (PTP) in neoplastic models.
  • 1 Author merit

Education

PhD, University of Torino, Italy, 1996

Lab information

Andrea Rasola lab
http://www.biomed.unipd.it/people/rasola-andrea/

1 Protocol published
Analysis of the Effects of Hexokinase 2 Detachment From Mitochondria-Associated Membranes with the Highly Selective Peptide HK2pep
Authors:  Francesco Ciscato, Federica Chiara, Riccardo Filadi and Andrea Rasola, date: 07/20/2021, view: 808, Q&A: 0

The crucial role of hexokinase 2 (HK2) in the metabolic rewiring of tumors is now well established, which makes it a suitable target for the design of novel therapies. However, hexokinase activity is central to glucose utilization in all tissues;

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