Stephan Urban University Hospital Heidelberg Heidelberg
2 protocols

Benno Zehnder University Hospital Heidelberg Heidelberg
1 protocol

Thomas Tu
  • Research scientist, University of Sydney and Westmead Institute for Medical Research Westmead
Research focus
  • ● Molecular mechanisms of hepatitis B virus (HBV) infection persistence and HBV DNA integration.
    ● Long-term host-virus interactions and their roles in disease progression during chronic HBV infection.
    ● Early stages of liver cancer initiation and the clonal expansion of phenotypically altered hepatocytes.
  • 1 Author merit
1 Protocol published
A Sensitive and Specific PCR-based Assay to Quantify Hepatitis B Virus Covalently Closed Circular (ccc) DNA while Preserving Cellular DNA
Authors:  Benno Zehnder, Stephan Urban and Thomas Tu, date: 04/20/2021, view: 2581, Q&A: 0

Hepatitis B virus (HBV) is the major cause of liver diseases and liver cancer worldwide. After infecting hepatocytes, the virus establishes a stable episome (covalently closed circular DNA, or cccDNA) that serves as the template for all viral

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