Siou Ku
  • 2 Author merit
2 Protocols published
Determination of Microtubule Lattice Parameters from Cryo-electron Microscope Images Using TubuleJ
Authors:  Siou Ku, Cédric Messaoudi, Charlotte Guyomar, Charles Kervrann and Denis Chrétien, date: 11/05/2020, view: 577, Q&A: 0

The α-β tubulin heterodimer undergoes subtle conformational changes during microtubule assembly. These can be modulated by external factors, whose effects on microtubule structure can be characterized on 2D views obtained by cryo-electron

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Microtubule Seeded-assembly in the Presence of Poorly Nucleating Nucleotide Analogues
Authors:  Siou Ku, Claire Heichette, Laurence Duchesne and Denis Chrétien, date: 08/20/2020, view: 825, Q&A: 0
Microtubule dynamic instability is driven by the hydrolysis of the GTP bound to the β-subunit of the α-β tubulin heterodimer. Nucleotide analogues are commonly used to mimic the different steps of the tubulin GTPase cycle, but most of them are poor ...
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