Wayne Lencer Gastroenterology, Boston Children's Hospital, Harvard Medical School, USA
2 protocols

Mariska Simpson GI Cell Biology, Boston Children's Hospital, 2018-2020
1 protocol

Phi Luong
  • Instructor, GI Cell Biology, Boston Children's Hospital, 2012-2020
Research focus
  • -
  • 1 Author merit

Education

PhD, UT Southwestern, USA, 2011

Publications

• Ouyang, H., Luong, P., Frodin, M. and Hansen, S. H. (2020). p190A RhoGAP induces CDH1 expression and cooperates with E-cadherin to activate LATS kinases and suppress tumor cell growth. Oncogene.
• Luong, P., Li, Q., Chen, P. F., Wrighton, P. J., Chang, D., Dwyer, S., Bayer, M. T., Snapper, S. B., Hansen, S. H., Thiagarajah, J. R., Goessling, W. and Lencer, W. I. (2020). A quantitative single-cell assay for retrograde membrane traffic enables rapid detection of defects in cellular organization. Mol Biol Cell 31(7): 511-519.
• Grey, M. J., Cloots, E., Simpson, M. S., LeDuc, N., Serebrenik, Y. V., De Luca, H., De Sutter, D., Luong, P., Thiagarajah, J. R., Paton, A. W., Paton, J. C., Seeliger, M. A., Eyckerman, S., Janssens, S. and Lencer, W. I. (2020). IRE1beta negatively regulates IRE1alpha signaling in response to endoplasmic reticulum stress. J Cell Biol 219(2).
• Luong, P., Hedl, M., Yan, J., Zuo, T., Fu, T. M., Jiang, X., Thiagarajah, J. R., Hansen, S. H., Lesser, C. F., Wu, H., Abraham, C. and Lencer, W. I. (2018). INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. Elife 7.
• Frank, S. R., Kollmann, C. P., Luong, P., Galli, G. G., Zou, L., Bernards, A., Getz, G., Calogero, R. A., Frodin, M. and Hansen, S. H. (2018). Correction: p190 RhoGAP promotes contact inhibition in epithelial cells by repressing YAP activity. J Cell Biol 217(9): 3313.
• Yu, X., Woolery, A. R., Luong, P., Hao, Y. H., Grammel, M., Westcott, N., Park, J., Wang, J., Bian, X., Demirkan, G., Hang, H. C., Orth, K. and LaBaer, J. (2014). Copper-catalyzed azide-alkyne cycloaddition (click chemistry)-based detection of global pathogen-host AMPylation on self-assembled human protein microarrays. Mol Cell Proteomics 13(11): 3164-3176.
• Bu, Q., Lv, T., Shen, H., Luong, P., Wang, J., Wang, Z., Huang, Z., Xiao, L., Engineer, C., Kim, T. H., Schroeder, J. I. and Huq, E. (2014). Regulation of drought tolerance by the F-box protein MAX2 in Arabidopsis. Plant Physiol 164(1): 424-439.
• Grammel, M., Luong, P., Orth, K. and Hang, H. C. (2011). A chemical reporter for protein AMPylation. J Am Chem Soc 133(43): 17103-17105.
• Hao, Y. H., Chuang, T., Ball, H. L., Luong, P., Li, Y., Flores-Saaib, R. D. and Orth, K. (2011). Characterization of a rabbit polyclonal antibody against threonine-AMPylation. J Biotechnol 151(3): 251-254.
• Woolery, A. R., Luong, P., Broberg, C. A. and Orth, K. (2010). AMPylation: Something Old is New Again. Front Microbiol 1: 113.
• Luong, P., Kinch, L. N., Brautigam, C. A., Grishin, N. V., Tomchick, D. R. and Orth, K. (2010). Kinetic and structural insights into the mechanism of AMPylation by VopS Fic domain. J Biol Chem 285(26): 20155-20163.
• Shen, H., Zhu, L., Bu, Q. Y. and Huq, E. (2012). MAX2 affects multiple hormones to promote photomorphogenesis. Mol Plant 5(3): 750-762.
1 Protocol published
A Quantitative Single-cell Flow Cytometry Assay for Retrograde Membrane Trafficking Using Engineered Cholera Toxin
Authors:  Mariska Simpson, Wayne I. Lencer and Phi Luong, date: 08/05/2020, view: 685, Q&A: 0
The organization and distribution of proteins, lipids, and nucleic acids in eukaryotic cells is an essential process for cell function. Retrograde trafficking from the plasma membrane to the Golgi and endoplasmic reticulum can greatly modify cell ...
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