Swee Lay Thein —BIO-PROTOCOL

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Laurel Mendelsohn Sickle Cell Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda
1 protocol

Venina Dominical National Heart, Lung, and Blood Institute, NIH Bethesda
1 protocol

Emilia Barbu National Heart, Lung, and Blood Institute, NIH Bethesda
1 protocol

Swee Lay Thein

Senior Investigator and Branch Chief, National Heart, Lung and Blood Institute / NIH Bethesda

Research focus

The pathophysiology of sickle cell disease (SCD) - applying insights from genetics and genomics and genotype-phenotype observations to accelerate translation of basic discovery to therapeutic applications.

1 Author merit
Reviewer merit
Editor merit

Education

M.B.,B.S., University of Malaya, 1976

Lab information

Swee Lay Thein lab

Publications

https://www.ncbi.nlm.nih.gov/sites/myncbi/swee%20lay.thein.1/bibliography/52510958/public/?sort=date&direction=descending

1 Protocol published

An Imaging Flow Cytometry Method to Measure Citrullination of H4 Histone as a Read-out for Neutrophil Extracellular Traps Formation

Authors: Emilia A. Barbu, Venina M. Dominical, Laurel Mendelsohn and Swee Lay Thein, date: 02/20/2021, view: 576, Q&A: 0

The formation of neutrophil extracellular traps (NETs) is thought to play a critical role in infections and propagating sterile inflammation. Histone citrullination is an essential and early step in NETs formation, detectable prior to the formation

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