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Lai Chu Wu
Rheumatology & Immunology, Ohio State University Wexner Medical Center, Columbus
1 protocol
Caitlin Henry
Rheumatology & Immunology, Ohio State University Wexner Medical Center, Columbus
1 protocol
Abigail Foster
Rheumatology & Immunology, Ohio State University Wexner Medical Center, Columbus
1 protocol
William Willis
Rheumatology & Immunology, Ohio State University Wexner Medical Center, Columbus
1 protocol
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Wael Jarjour
Rheumatology & Immunology, Ohio State University Wexner Medical Center, Columbus
Research focus
Biochemistry
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1 Protocol published
In vitro
Crosslinking Reactions and Substrate Incorporation Assays for The Identification of Transglutaminase-2 Protein Substrates
Authors:
William L. Willis
,
Abigail Foster
,
Caitlin Henry
,
Lai Chu Wu
and
Wael Jarjour
,
date:
06/20/2020,
view:
1617,
Q&A:
0
Transglutaminase (TG2) catalyzes protein crosslinking between glutamyl and lysyl residues. Catalytic activity occurs via a transamidation mechanism resulting in the formation of isopeptide bonds. Since TG2-mediated transamidation is of mechanistic ...
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