Alfano Luigi National Cancer Institute Pascale Foundation
2 protocols

Antonio Giordano Professor, Department of Biology and Medicine, Temple University, Pennsylvania (PA), 2001-2000; Director, Sbarro Health Research Organization, Temple University, Pennsylvania (PA),2000
2 protocols

Francesca Pentimalli Group Leader, National Cancer Institute of Naples, IRCCS Pascale Foundation, CROM, Oncology Research Center of Mercogliano, Italy, 2007-
2 protocols


Angela Altieri
  • Post doctoral researcher, Cancer Research and Molecular Medicine, Sbarro Institute, Philadelphia, 2016-2020
Research focus
  • Cancer biology
  • 1 Author merit

Education

PhD in Genetics, Oncology and Clinical Medicine, University of Siena , Italy, 2019

Publications

• Alfano, L., Costa, C., Caporaso, A., Altieri, A., Indovina, P., Macaluso, M., Giordano, A. and Pentimalli, F. (2016). NONO regulates the intra-S-phase checkpoint in response to UV radiation. Oncogene 35(5): 567-576.
• Alfano, L., Caporaso, A., Altieri, A., Costa, C., Forte, I. M., Iannuzzi, C. A., Barone, D., Esposito, L., Giordano, A. and Pentimalli, F. (2018). NONO ubiquitination is mediated by FBW7 and GSK3 beta via a degron lost upon chromosomal rearrangement in cancer. J Cell Physiol 233(5): 4338-4344.
• Alfano, L., Caporaso, A., Altieri, A., Dell'Aquila, M., Landi, C., Bini, L., Pentimalli, F. and Giordano, A. (2019). Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation. Nucleic Acids Res 47(8): 4068-4085.
1 Protocol published
SMART (Single Molecule Analysis of Resection Tracks) Technique for Assessing DNA end-Resection in Response to DNA Damage
DNA double strand breaks (DSBs) are among the most toxic lesions affecting genome integrity. DSBs are mainly repaired through non-homologous end joining (NHEJ) and homologous recombination (HR). A crucial step of the HR process is the generation, ...
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