Yunlong Ma
  • Faculty, Wenzhou Medical University
Research focus
  • Cancer biology
  • 1) Somatic mutation and methylation for diagnosis cancer based on cfDNA and tissue samples. 2) Integrative genomics analysis identifies risk genes for psychiatric disorders based on GWAS, eQTL and other omics data.


PhD, Zhejiang University, 2017

Lab information

Jianzhong Su Lab


1.Ma Y, Li J, Xu Y, Wang Y, Yao Y, Liu Q, Wang M, Zhao X, Fan R, Chen J, Han H, Yang Z, Cui W, Yuan W, Gao H, Chen X, Ning Y, Ma J, Payne T, Li M#. Identification of 34 genes conferring genetic and pharmacological risk for the comorbidity of schizophrenia and smoking behaviors. Aging-US 2020 Feb 3;12(3):2169-2225. doi: 10.18632/aging.102735.
2.Yao Y, Xu Y, Cai Z, Liu Q, Ma Y, Li A, Payne T, Li M#. Determination of Shared Genetic Etiology and Possible Causal Relations Between Tobacco Smoking and Depression. Psychological Medicine 2020 Apr 6;1-10. doi: 10.1017/S003329172000063X.
3.Fan R, Cui W, Chen J, Ma Y, Yang Z, Payne T, Ma J, Li M#. Gene-based Association Analysis Reveals Involvement of LAMA5 and Cell Adhesion Pathways in Nicotine Dependence in African- And European-American Samples. Addiction Biology 2020 Apr 13;e12898. doi: 10.1111/adb.12898.
4.Xu Y, Cao L, Zhao X, Yao Y, Liu Q, Zhang B, Wang Y, Mao Y, Ma Y, Ma J, Payne J, Li L#, Li M#. Prediction of Smoking Behavior from Single-Nucleotide Polymorphisms with Machine Learning Approaches. Frontiers in Psychiatry 2020.
5.Wang M, Zhao J, Wang Y, Mao Y, Zhao X, Huang P, Liu Q, Ma Y, Yao Y, Yang Z, Yuan W, Cui W, Payne J, Li M#. Genome-wide DNA methylation analysis reveals significant impact of long-term ambient air pollution exposure on biological functions related to mitochondria and immune response. Environmental Pollution 2020.
6.Liu Q, Hou A, Zhang Y, Guo Y, Li J, Yao Y, Niu K, Li H, Ma Y#, Cao J#. MiR-190a potentially ameliorates postoperative cognitive dysfunction by regulating Tiam1. BMC Genomics 2019 Aug 22;20(1):670. doi: 10.1186/s12864-019-6035-0.
7.Liu Q, Xu Yi, Mao Y, Ma Y, Wang M, Han H, Cui W, Yuan W, Payne T, Xu Y, Li M#, Yang Z#. Genetic and Epigenetic Analysis Revealing Variants in the NCAM1-TTC12-ANKK1-DRD2 Cluster Associated Significantly With Nicotine Dependence in Chinese Han Smokers. Nicotine & Tobacco Research 2019 Dec 23; ntz240. doi: 10.1093/ntr/ntz240.
8.Chen L, Yao Y, Jin C, Wu S, Liu Q, Li J, Ma Y, Xu Y, Zhong Y#. Integrative Genomic Analysis Identified Common Regulatory Networks Underlying the Correlation Between Coronary Artery Disease and Plasma Lipid Levels. BMC Cardiovascular Disorders 2019 Dec 23;19(1):310. doi: 10.1186/s12872-019-01271-9.
9.Chen J, Ma Y, Fan R, Yang Z, Li M#. Implication of Genes for the N-Methyl-D-Aspartate (NMDA) Receptor in Substance Addictions. Molecular Neurobiology 2018 Sep;55(9):7567-7578. doi: 10.1007/s12035-018-0877-3.
10.Han H*, Liu Q*, Yang Z, Wang M, Ma Y, Cao L, Cui W, Yuan W, Payne T, Li L, Li M#. Association and cis-mQTL Analysis of Variants in Serotonergic Genes Associated With Nicotine Dependence in Chinese Han Smokers. Translational Psychiatry 2018 Nov 7;8(1):243. doi: 10.1038/s41398-018-0290-8.
11.Yao Y, Xu Y, Zhao J, Ma Y, Su K, Yuan W, Ma J, Payne T, Li M#. Detection of Significant Association Between Variants in Cannabinoid Receptor 1 Gene ( CNR1) and Personality in African-American Population. Frontiers in Genetics 2018 Jun 14;9:199. doi: 10.3389/fgene.2018.00199.
12.Liu Q*, Han H*, Wang M, Yao Y, Wen Li, Jiang K, Ma Y, Fan R, Chen J, Su K, Yang Z, Cui W, Yuan W, Jiang X, Li J, Payne T, Wang J, Li M#. Association and cis-mQTL Analysis of Variants in CHRNA3-A5, CHRNA7, CHRNB2, and CHRNB4 in Relation to Nicotine Dependence in a Chinese Han Population. Translational Psychiatry 2018 Apr 18;8(1):83. doi: 10.1038/s41398-018-0130-x.
13.Ma Y, Wen L, Cui W, Yuan W, Yang Z, Jiang K, Jiang X, Huo M, Sun Z, Han H, Su K, Yang S, Payne T, Wang J#, Li M#. Prevalence of cigarette smoking and nicotine dependence in men and women residing in two provinces in China. Frontiers in Psychiatry 2017 Dec 1;8:254. doi: 10.3389/fpsyt.2017.00254.
14.Ma Y, Li M#. Establishment of a strong link of smoking with cancer pathogenesis through DNA methylation analysis. Scientific Reports 2017 May 12;7(1):1811. doi: 10.1038/s41598-017-01856-4.
15.Wen L, Han H, Liu Q, Su K, Yang Z, Cui W, Yuan W, Ma Y, Fan R, Chen J, Jiang K, Jiang X, Payne T, Wang J, Li M#. Significant association of the CHRNB3-CHRNA6 gene cluster with nicotine dependence in the Chinese Han population. Scientific Reports 2017 Aug 29;7(1):9745. doi: 10.1038/s41598-017-09492-8.
16.Ma Y, Yuan W, Cui W, Li M#. Meta-analysis reveals significant association of 3'-UTR VNTR in SLC6A3 with smoking cessation in Caucasian populations. The Pharmacogenomics Journal 2016 Feb;16(1):10-7. doi: 10.1038/tpj.2015.44.
17.Ma Y, Fan R, Li M#. Meta-Analysis Reveals Significant Association of the 3'-UTR VNTR in SLC6A3 With Alcohol Dependence. Alcoholism: Clinical and Experimental Research 2016 Jul;40(7):1443-53. doi: 10.1111/acer.13104.
18.Wang M, Ma Y, Yuan W, Su K, Li M#. Meta-Analysis of the COMT Val158Met Polymorphism in Major Depressive Disorder: Effect of Ethnicity. Journal of Neuroimmune Pharmacology 2016 Sep;11(3):434-45. doi: 10.1007/s11481-016-9651-3.
19.Ma Y, Wang M, Yuan W, Su K#, Li M#. The Significant Association of Taq1A Genotypes in DRD2/ANKK1 With Smoking Cessation in a Large-Scale Meta-Analysis of Caucasian Populations. Tranlational Psychiatry 2015 Dec 1;5(12):e686. doi: 10.1038/tp.2015.176.
20.Ma Y, Yuan Y, Jiang X, Cui W, Li M#. Updated Findings of the Association and Functional Studies of DRD2/ANKK1 Variants With Addictions. Molecular Neurobiology 2015 Feb;51(1):281-99. doi: 10.1007/s12035-014-8826-2.
Jiang X, Ma Y, Cui W, Li M#. Association of Variants in HLA-DP on Chromosome 6 With Chronic Hepatitis B Virus Infection and Related Phenotypes. Amino Acids 2014 Aug;46(8):1819-26. doi: 10.1007/s00726-014-1767-2.
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