Peter Krammer Immunogenetics, German Cancer Research Center, Heidelberg
1 protocol

Corinna Link DKFZ-Bayer Joint Immunotherapy Laboratory, German Cancer Research Center
1 protocol

Kevin Bode Immunobiology, Joslin Diabetes Center, 2020
1 protocol

Heiko Weyd
  • Groupleader, Immunogenetics, German Cancer Research Institute, 2006-2020
Research focus
  • Immunology
  • 1 Author merit

Education

PhD, Hamburg University, 2005

Publications

• Klein, M. A., Kaeser, P. S., Schwarz, P., Weyd, H., Xenarios, I., Zinkernagel, R. M., Carroll, M. C., Verbeek, J. S., Botto, M., Walport, M. J., Molina, H., Kalinke, U., Acha-Orbea, H. and Aguzzi, A. (2001). Complement facilitates early prion pathogenesis. Nat Med 7(4): 488-492.
• Lavrik, I., Krueger, A., Schmitz, I., Baumann, S., Weyd, H., Krammer, P. H. and Kirchhoff, S. (2003). The active caspase-8 heterotetramer is formed at the CD95 DISC. Cell Death Differ 10(1): 144-145.
• Schmitz, I., Weyd, H., Krueger, A., Baumann, S., Fas, S. C., Krammer, P. H. and Kirchhoff, S. (2004). Resistance of short term activated T cells to CD95-mediated apoptosis correlates with de novo protein synthesis of c-FLIPshort. J Immunol 172(4): 2194-2200.
• Weyd, H., Abeler-Dorner, L., Linke, B., Mahr, A., Jahndel, V., Pfrang, S., Schnolzer, M., Falk, C. S. and Krammer, P. H. (2013). Annexin A1 on the surface of early apoptotic cells suppresses CD8+ T cell immunity. PLoS One 8(4): e62449.
• Abeler-Dorner, L., Rieger, C. C., Berger, B., Weyd, H., Graf, D., Pfrang, S., Tarner, I. H., Schwarting, A., Lorenz, H. M., Muller-Ladner, U., Krammer, P. H. and Kuhn, A. (2013). Interferon-alpha abrogates the suppressive effect of apoptotic cells on dendritic cells in an in vitro model of systemic lupus erythematosus pathogenesis. J Rheumatol 40(10): 1683-1696.
• Kuhn, A., Wenzel, J. and Weyd, H. (2014). Photosensitivity, apoptosis, and cytokines in the pathogenesis of lupus erythematosus: a critical review. Clin Rev Allergy Immunol 47(2): 148-162.
• Linke, B., Abeler-Dorner, L., Jahndel, V., Kurz, A., Mahr, A., Pfrang, S., Linke, L., Krammer, P. H. and Weyd, H. (2015). The tolerogenic function of annexins on apoptotic cells is mediated by the annexin core domain. J Immunol 194(11): 5233-5242.
• Schmidt, A., Eriksson, M., Shang, M. M., Weyd, H. and Tegner, J. (2016). Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate. PLoS One 11(2): e0148474.
• Weyd, H. (2016). More than just innate affairs - on the role of annexins in adaptive immunity. Biol Chem 397(10): 1017-1029.
• Krammer, P. H. and Weyd, H. (2017). Life, death and tolerance. Biochem Biophys Res Commun 482(3): 470-472.
• Bode, K., Bujupi, F., Link, C., Hein, T., Zimmermann, S., Peiris, D., Jaquet, V., Lepenies, B., Weyd, H. and Krammer, P. H. (2019). Dectin-1 Binding to Annexins on Apoptotic Cells Induces Peripheral Immune Tolerance via NADPH Oxidase-2. Cell Rep 29(13): 4435-4446 e4439.
1 Protocol published
Flow-cytometric Detection of Low-level Reactive Oxygen Species in Cell Lines and Primary Immune Cells
Authors:  Kevin Bode, Corinna Link, Peter H. Krammer and Heiko Weyd, date: 09/05/2020, view: 1077, Q&A: 0
Depending on its concentration and cellular origin the production of reactive oxygen species (ROS) in the organism serves a variety of functions. While high concentrations during an oxidative burst are used to fight pathogens, low to moderate ...
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