Elena Mercade Department of Biology, Healthcare and the Environment, University of Barcelona
1 protocol

Carla Pérez-Cruz Department of Biology Health and Environment, University, Barcelona
1 protocol

Nicolás Baeza Department of Biology Health and Environment, University of Barcelona, Barcelona
1 protocol

Lidia Delgado Scientific and Technological Centers University of Barcelona
1 protocol

Carmen López-Iglesias
  • Associate professor, Maastricht Multimodal Molecular Imaging Institute M4I , university of maastricht, 2015-2019
Research focus
  • -
  • 1 Author merit

Education

Dr., University of Oviedo, Spain, 1985

Publications

Since 2017
• Artegiani B, van Voorthuijsen L, Lindeboom RGH, Seinstra D, Heo I, Tapia P, López-Iglesias C, Postrach D, Dayton T, Oka R, Hu H, van Boxtel R, van Es JH, Offerhaus J, Peters PJ, van Rheenen J, Vermeulen M, Clevers H. Cell Stem Cell. 2019 Jun 6;24(6):927-943.e6. doi: 10.1016/j.stem.2019.04.017.
• Boonekamp KE, Kretzschmar K, Wiener DJ, Asra P, Derakhshan S, Puschhof J, López-Iglesias C, Peters PJ, Basak O, Clevers H. Proc Natl Acad Sci U S A. 2019 Jun 28. pii: 201715272. doi: 10.1073/pnas.1715272116 Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids.
• Hu H, Gehart H, Artegiani B, LÖpez-Iglesias C, Dekkers F, Basak O, van Es J, Chuva de Sousa Lopes SM, Begthel H, Korving J, van den Born M, Zou C, Quirk C, Chiriboga L, Rice CM, Ma S, Rios A, Peters PJ, de Jong YP, Clevers H. Cell. 2018 Nov 29;175(6):1591-1606.e19. doi: 10.1016/j.cell.2018.11.013 Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures.
• Gemmink A, Daemen S, Kuijpers HJH, Schaart G, Duimel H, López-Iglesias C, van Zandvoort MAMJ, Knoops K, Hesselink MKC. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Nov;1863(11):1423-1432. doi: 10.1016/j.bbalip.2018.08.016. Epub 2018 Aug 31. Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids.
• Vorselen D, Marchetti M, López-Iglesias C, Peters PJ, Roos WH, Wuite GJL. Nanoscale. 2018 Mar 15;10(11):5318-5324. doi: 10.1039/c7nr09224e. Super-resolution microscopy localizes perilipin 5 at lipid droplet-mitochondria interaction sites and at lipid droplets juxtaposing to perilipin 2.
• Fleta-Soriano E, Smutná K, Martínez JP, Lorca Oró C, Sadiq SK, Mirambeau G, Lopez-Iglesias C, Bosch M, Pol A, Brönstrup M, Diez J, Meyerhans A. Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00739-17. doi: 10.1128/AAC.00739-17. Print 2017 Aug Multilamellar nanovesicles show distinct mechanical properties depending on their degree of lamellarity.
• Gremer L, Schölzel D, Schenk C, Reinartz E, Labahn J, Ravelli RBG, Tusche M, Lopez-Iglesias C, Hoyer W, Heise H, Willbold D, Schröder GF. Science. 2017 Oct 6;358(6359):116-119. doi: 10.1126/science.aao2825. Epub 2017 Sep 7. The Myxobacterial Metabolite Soraphen A Inhibits HIV-1 by Reducing Virus Production and Altering Virion Composition.
• Gonçalves FDC, Luk F, Korevaar SS, Bouzid R, Paz AH, López-Iglesias C, Baan CC, Merino A, Hoogduijn MJ. Sci Rep. 2017 Sep 21;7(1):12100. doi: 10.1038/s41598-017-12121-z. Fibril structure of amyloid-β(1-42) by cryo-electron microscopy.
• Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Sci Rep. 2017 Nov 10;7(1):15297. doi: 10.1038/s41598-017-15717-7. Membrane particles generated from mesenchymal stromal cells modulate immune responses by selective targeting of pro-inflammatory monocytes.
1 Protocol published
Cryo-transmission Electron Microscopy of Outer-inner Membrane Vesicles Naturally Secreted by Gram-negative Pathogenic Bacteria
A protocol was developed to visualize and analyze the structure of membrane vesicles (MVs) from Gram-negative bacteria. It is now accepted that these micrometric spherical vesicles are commonly produced by cells from all three domains of life, so ...
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