Education
Ph.D., Martin-Luther University, Germany, 2015
Lab information
Saulius Sumanas Lab
https://www.cincinnatichildrens.org/research/divisions/d/dev-biology/labs/sumanas
Research focus
Cardiovascular Development, Vascular Biology, Vascular regeneration, Genetics, Molecular Biology, Genome editing techniques
Publications
1. Metikala S, Neuhaus H, Hollemann T. A multichannel computer-driven system to raise aquatic embryos under selectable hypoxic conditions. Hypoxia (Auckl). 2018;6:1-9. doi: 10.2147/HP.S151536. eCollection 2018. PubMed PMID: 29392150; PubMed Central PMCID: PMC5769780.
2. Webb BD, Metikala S, Wheeler PG, Sherpa MD, Houten SM, Horb ME, Schadt EE. Heterozygous Pathogenic Variant in DACT1 Causes an Autosomal-Dominant Syndrome with Features Overlapping Townes-Brocks Syndrome. Hum Mutat. 2017 Apr;38(4):373-377. doi: 10.1002/humu.23171. Epub 2017 Feb 2. PubMed PMID: 28054444; PubMed Central PMCID: PMC5390682.
3. Lokapally A, Metikala S, Hollemann T. Xenopus laevis neuronal cell adhesion molecule (nrcam): plasticity of a CAM in the developing nervous system. Dev Genes Evol. 2017 Jan;227(1):61-67. doi: 10.1007/s00427-016-0569-9. Epub 2016 Dec 10. PubMed PMID: 27942869.
4. Metikala S, Neuhaus H, Hollemann T. Suppression of vascular network formation by chronic hypoxia and prolyl-hydroxylase 2 (phd2) deficiency during vertebrate development. Angiogenesis. 2016 Apr;19(2):119-31. doi: 10.1007/s10456-015-9492-3. Epub 2015 Dec 17. PubMed PMID: 26678600.
5. Lokapally A, Metikala S, Hollemann T. Expressional characterization of mRNA (guanine-7) methyltransferase (rnmt) during early development of Xenopus laevis. Int J Dev Biol. 2016;60(1-3):65-9. doi: 10.1387/ijdb.150409th. PubMed PMID: 27002806.
6. Govindan R, Suran S, Metikala S. Gene Silencing - Targeting at Gene Methylation and Demethylation Patterns for the Arrest of Cancer Progression. Journal of cancer science & therapy. 2014 April; :174-176. doi: 10.4172/1948-5956.1000268.
7. Neuhaus H, Metikala S, Hollemann T. Xenopus cadherin 5 is specifically expressed in endothelial cells of the developing vascular system. Int J Dev Biol. 2014;58(1):51-6. doi: 10.1387/ijdb.140013hn. PubMed PMID: 24860995.