Eva Hedlund Department of Neuroscience, Karolinska Institute
1 protocol

Julio Aguila Karolinska Institutet, Stockholm
1 protocol

Jik Nijssen
  • Graduate Student, Neuroscience, Karolinska Institutet
Research focus
  • -
  • 1 Author merit


M.Sc., Maastricht University, Netherlands, 2015


· Allodi I, Nijssen J, Aguila Benitez J, Schweingruber C, Fuchs A, Bonvicini G, Cao M, Kiehn O, Hedlund E. Modeling motor neuron resilience in ALS using stem cells. Stem Cell Rep. 2019, 12(6): 1329-1341. IF: 7.338
· Nijssen J, Aguila Benitez J, Hoogstraaten R, Kee N, Hedlund E. Axon-seq decodes the motor axon transcriptome and its modulation in response to ALS. Stem Cell Rep. 2018, 11(6): 1565-1578. IF: 7.338
· Harald Lund Lund H, Pieber M, Parsa R, Grommsich D Ewing E, Kular L, Han J, Zhu K, Nijssen J, Hedlund E, Needhamsen M, Ruhrmann S, Guerreiro-Cacais AO, Berglund R, Forteza MJ, Ketelhuth DFJ, Butovsky O, Jagodic M, Zhang XM, Harris RA. Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling. Nat. Immun. 2018, 19(5): 1-7. IF: 21.809
· Nijssen J*, Comley LH, Hedlund E*. Motor neuron vulnerability and resistance in amyotrophic lateral sclerosis. Acta Neuropathol. 2017, 133: 863-885. IF: 15.872 *corresponding author.
· Comley LH, Nijssen J, Frost-Nylen J, Hedlund E. Cross-disease comparison of amyotrophic lateral sclerosis and spinal muscular atrophy reveals conservation of selective vulnerability but differential neuromuscular junction pathology. J. Comp. Neurol. 2016, 524(7): 1424-42. IF: 3.400
1 Protocol published
Axon-seq for in Depth Analysis of the RNA Content of Neuronal Processes
Authors:  Jik Nijssen, Julio Aguila and Eva Hedlund, date: 07/20/2019, view: 8200, Q&A: 0
Neuronal processes have an RNA composition that is distinct from the cell body. Therefore, to fully understand neuronal biology in health and disease we need to study both somas, dendrites and axons. Here we describe a detailed protocol of a newly ...
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