Sotiris Hadjikakou Deaprtment of Chemisty, University of Ioannina, Ioannina
1 protocol

Christina N. Banti
  • Adjunct Lecturer, Deaprtment of Chemisty, University of Ioannina, Ioannina
Research focus
  • -
  • 1 Author merit

Education

Ph.D., Medical School, University of Ioannina, 2014

Publications

· "Synthesis, characterization and biological evaluation of novel antimony(III) iodide complexes with tetramethylthiourea and N-ethylthiourea", I.I. Ozturk, S. Yarar, M. Gürgan, D. Ceyhan, C.N. Banti, S.K. Hadjikakou, M. Manoli, E. Moushi, A.J. Tasiopoulos, Inorg Chim Acta, 2019, 491, 14–24
· "The periodic table of urea derivative: small molecules of zinc(II) and nickel(II) of diverse antimicrobial and antiproliferative applications", C.N. Banti, M. Poyraz, I. Sainis, M. Sari, G. Rossos, N. Kourkoumelis,• S.K. Hadjikakou, Molecular Diversity, 2019, https://doi.org/10.1007/s11030-018-09909-0
· "Anti-proliferative and antitumor activity of organotin(IV) compounds. An overview of the last decade and future perspectives", C.N. Banti, S.K. Hadjikakou, T. Sismanoglu, N. Hadjiliadis, J. Inorg. Biochem., 2019, 194, 114–152
· "Diclofenac conjugates with biocides through silver(I) ions (CoMeD's); Development of a reliable model for the prediction of anti-proliferation of NSAID's-silver formulations", C.N. Banti, A.G. Hatzidimitriou, N. Kourkoumelis, S.K. Hadjikakou, J. Inorg. Biochem., 2019, 194, 7–18
· "Non steroidal anti-inflammatory drug (NSAIDs) in breast cancer chemotherapy; antimony(V) salicylate a DNA binder", N.M. Polychronis, C.N. Banti, C.P. Raptopoulou, V. Psycharis, N. Kourkoumelis, S.K. Hadjikakou, Inorg Chim Acta, 2019, 489, 39–47
· "Editorial Preface to “A Commemorative Issue in Honour of Professor Nick Hadjiliadis: Metal Complex Interactions with Nucleic Acids and/or DNA” Christina N. Banti and Sotiris K. Hadjikakou, Int. J. Mol. Sci. 2018, 19, 3815
· "Bismuth(III) bromide-thioamide complexes: synthesis, characterization and cytotoxic properties", M. Cakmak, I.I. Ozturk, C.N. Banti, M. Manoli, E. Moushi, A.J. Tasiopoulos, A.M. Grześkiewicz, M. Kubicki,S.K. Hadjikakou, Main Group Met. Chem. 2018, 41, 143–154
· "A water-soluble silver(I) formulation as an effective disinfectant of contactlenses cases" M.P. Chrysouli, C.N. Banti, Ι. Milionis, D. Koumasi, C.P. Raptopoulou, V. Psycharis,I. Sainis, S.K. Hadjikakou, Mater Sci Eng C Mater Biol Appl, 2018, 93, 902–910
· " Poly Organotin Acetates against DNA with Possible Implementation on Human Breast Cancer," G.K. Latsis, C.N. Banti, N. Kourkoumelis, C. Papatriantafyllopoulou, N. Panagiotou, A. Tasiopoulos, A. Douvalis, A.G. Kalampounias, T. Bakas, S.K. Hadjikakou, Int. J. Mol. Sci. 2018, 19, 2055-2072
· "Silver complex of salicylic acid and its hydrogel-cream in wound healing chemotherapy", M.-E.K. Stathopoulou, C.N. Banti, N. Kourkoumelis, A.G. Hatzidimitriou, A.G. Kalampounias, S.K. Hadjikakou, J Inorg Biochem, 2018, 181, 41–55
· "Silver ciprofloxacin (CIPAG): a successful combination of chemically modified antibiotic in inorganic–organic hybrid, I. Milionis, C.N. Banti, I. Sainis, C.P. Raptopoulou, V. Psycharis, N. Kourkoumeli and S.K. Hadjikakou, J Biol Inorg Chem, 2018, 23, 705–723
· "Innovative material containing the natural product curcumin, with enhanced antimicrobial properties for active packaging", A. Papadimitriou, I. Ketikidis, M.K. Stathopoulou, C.N. Banti, C. Papachristodoulou, L. Zoumpoulakis, S. Agathopoulos, G.V. Vagenas, S.K. Hadjikakou, Mater Sci Eng C Mater Biol Appl, 2018, 84, 118-122
· "Chloro(triphenylphosphine)gold(I) a forefront reagent in gold chemistry as apoptotic agent for cancer cells", M.P. Chrysouli, C.N. Banti, N. Kourkoumelis, N. Panayiotou, A.J. Tasiopoulos, S.K. Hadjikakou, J Inorg Biochem, 2018, 179, 107-120
· "New metalo-therapeutics of NSAIDs against human breast cancer cells", C.N. Banti, C. Papatriantafyllopoulou, A.J. Tasiopoulos, S.K. Hadjikakou, Eur. J. Med. Chem., 2018, 143, 1687-1701
· "Synthesis, Characterization and Cytostatic Properties of Bismuth(III) Chloride Complexes with Heterocyclic Thioamides; A survey for Structure Activity Relationship", S. Yarar, I.I. Ozturk, C.N. Banti, N. Panagiotou, C. Papatriantafyllopoulou, M. Manoli, M.J. Manos, A.J. Tasiopoulos, S.K. Hadjikakou, Inorg Chim Acta, 2018, 471, 23-33
· 'Synthesis, characterization and biological activities of copper(II) complex of 2-Benzimidazolyl-urea and the nitrate salt of 2-Benzimidazolyl-urea", Mehmet Poyraz, Musa Sari, Christina N. Banti and Sotiris K. Hadjikakou, J Mol Struct., 2017, 1146, 809-813
· "N-(4-Hydroxyphenyl)acetamide against diiodine towards polyiodide dianion", Christina N. Banti, Nick Kourkoumelis, Catherine P. Raptopoulou, Vassilis Psycharis, Sotiris K. Hadjikakou, New J. Chem., 2017, 41, 5555-5564
· "Synthesis characterization and biological activity of mixed ligand silver(I) complex of 2-Benzimidazolyl-urea and triphenylphosphine", M. Poyraz, H. Berber, C.N. Banti, N. Kourkoumelis, M.J. Manos, S.K. Hadjikakou, Polyhedron, 2017, 128, 95–103
· "QSAR studies on antimony(III) halide complexes with N-substituted thiourea derivatives", I.I. Ozturk, S. Yarar, C.N. Banti, N. Kourkoumelis, M.P. Chrysouli, M. Manoli, A. J. Tasiopoulos, S.K. Hadjikakou, Polyhedron, 2017, 123, 152-161
· "Silver(I) complexes of methyl xanthate against human adenocarcinoma breast cancer cells, Christina N. Banti, Nikolaos Kourkoumelis, Constantinos G. Tsiafoulis, Stavroula Skoulika, Sotiris K. Hadjikakou, Polyhedron, 2017, 121, 115-122
· "Platinum(II)-thiosemicarbazone metal-drugs override the cell resistance due to glutathione; Assessment of their activity against human adenocarcinoma cells, M. Poyraz, S. Demirayak, C.N. Banti, M.J Manos N. Kourkoumelis and S.K. Hadjikakou, J. Coord. Chem., 2016, 69, 3560-3579
· "Structural, photolysis and biological studies of novel mixed metal Cu(I)-Sb(III) mixed ligand complexes", V. Tsiatouras, C.N. Banti, A.M. Grześkiewicz, G. Rossos, N. Kourkoumelis, M. Kubicki and S.K. Hadjikakou, Journal of Photochemistry & Photobiology, B: Biology, 2016, 163, 261-268
· "Nimesulide silver metallodrugs, containing the mitochondriotropic, triaryl derivatives of pnictogen; Anticancer activity against human breast cancer cells", Christina N. Banti, Constantina Papatriantafyllopoulou, Maria Manoli, Anastasios J. Tasiopoulos and Sotiris K. Hadjikakou, Inorg. Chem., 2016, 55 (17), 8681–8696
· "Functionalized non steroidal anti-inflammatory drugs (NSAIDs) by metal ions with involvement on the cellular level", Christina N. Banti, Sotiris K. Hadjikakou, Eur. J. Inorg. Chem. 2016, 3048–3071
· "Novel bismuth(III) bromide or iodide compounds; Synthesis, characterization and biological activity against human adenocarcinoma cell lines", M. Arda, I.I. Ozturk, C.N. Banti, N. Kourkoumelis, M. Manoli, A.J. Tasiopoulos, S.K. Hadjikakou, RCS Advances, 2016, 6, 29026-29044
· "Addition of Tetraethylthiuram Disulfide to Antimony(III) Iodide; Synthesis, Characterization and Biological Activity", O.S. Urgut, I.I. Ozturk, C.N. Banti, N. Kourkoumelis, M. Manoli, A.J. Tasiopoulos, S.K. Hadjikakou, Inorg. Chim. Acta, 2016, 443, 141-150
· " New antibacterial, non-genotoxic materials, derived from the functionalization of the anti-thyroid drug methimazole with silver ions", I. Sainis, C.N. Banti, A.M. Owczarzak, L. Kyros, N. Kourkoumelis, M. Kubicki, S.K. Hadjikakou, J Inorg Biochem., 2016, 160, 114–124
· "New Antimony(III) Halide Complexes with Dithiocarbamate Ligands Derived from Thiuram Degradation: The Effect of the molecule's close contacts on in vitro cytotoxic activity", O.S. Urgut, I.I. Ozturk, C.N. Banti, N. Kourkoumelis, M. Manoli, A.J. Tasiopoulos, S.K. Hadjikakou, 2015, Mater Sci Eng C Mater Biol Appl 58 (2016) 396-408
· "Recent advances on antimony(III/V) compounds with potential activity against tumor cells", S.K. Hadjikakou, I.I. Ozturk, C.N. Banti, N. Kourkoumelis, N. Hadjiliadis, J Inorg Biochem. 2015,153, 293-305
· "Novel mixed metal Ag(I)-Sb(III)-metallotherapeutics of the NSAIDs, aspirin and salicylic acid: Enhancement of their solubility and bioactivity by using the surfactant CTAB", E.I. Gkaniatsou, C.N. Banti, N. Kourkoumelis, S. Skoulika, M. Manoli, A.J. Tasiopoulos, S.K. Hadjikakou, J Inorg Biochem. 2015, 150, 108-19
· "Mono-nuclear cis-Pd(II) chloride complex of the thio-nucleotide analogue 5-methyl-thiouracil and its biological activity", C.N. Banti, D.C. Charalampou, N. Kourkoumelis, A.M. Owczarzak, M. Kubicki, S.K. Hadjikakou, N. Hadjiliadis, Polyhedron, 2015, 87, 251-258
· "Silver(I) metallo-drugs of anti-inflammatory agents salicylic acid and its derivative which modulate cells function", C.N. Banti, A.D. Giannoulis, N. Kourkoumelis, A.M. Owczarzak, M. Kubicki and S.K. Hadjikakou, J. Inorg. Biochem., 2015, 142, 132–144
· "Antimony(III) halide compounds of thioureas: Structures and biological Activity", A. Han, I.I. Ozturk, C.N. Banti, N. Kourkoumelis, M. Manoli, A.J. Tasiopoulos, A.M. Owczarzak, M. Kubicki, S.K. Hadjikakou, Polyhedron 79 (2014) 151-160
· "A novel silver iodide metalo-drug: Experimental and computational modelling assessment of its interaction with intracellular DNA, lipoxygenase and glutathione", C.N. Banti, L. Kyros, G.D. Geromichalos, N. Kourkoumelis, M. Kubicki, S.K. Hadjikakou, European Journal of Medicinal Chemistry 77 (2014) 388-399
· "Novel metallo-therapeutics of the NSAID naproxen. Interaction with intracellular components that leads the cells to apoptosis", C.N. Banti, A.D. Giannoulis, N. Kourkoumelis, A. Owczarzak, M. Kubicki, S.K. Hadjikakou, Dalton Trans., 2014, 43, 6848-6863
· "Synthesis, antiradical activity and in vitro cytotoxicity of novel organotin complexes based on 2,6-di-tert-butyl-4-mercaptophenol", D.B. Shpakovsky, C.N. Banti, E.M. Mukhatova, Y.A. Gracheva, V.P. Osipova, N.T. Berberova, D.V. Albov, T.A. Antonenko, L. Aslanov, E.R. Milaeva, S.K. Hadjikakou, Dalton Trans., 2014, 43, 6880-6890
· "Assessment of organotins against the linoleic acid, glutathione and CT-DNA", C.N. Banti, E.I. Gkaniatsou, N. Kourkoumelis, M.J. Manos, A.J. Tasiopoulos, T. Bakas, S.K. Hadjikakou, Inorganica Chimica Acta , 2014, 2014, 423, 98-106
· "Synthesis, characterization, and binding properties towards CT-DNA and lipoxygenase of mixed-ligand silver(I) complexes with 2-mercaptothiazole and its derivatives and triphenylphosphine", L. Kyros, C.N. Banti, N. Kourkoumelis, M. Kubicki, I. Sainis, S.K. Hadjikakou, J Biol Inorg Chem, 2014, 19(3), 449-464
· "Synthesis, Structural Characterization and Cytostatic Properties of N,N-Dicyclohexyldithiooxamide Complexes of Antimony(III) Halides (SbX3, X: Br or I)", I.I. Ozturk, O.S. Urgut, C.N. Banti, N. Kourkoumelis, A.M. Owczarzak, M. Kubicki, S.K. Hadjikakou, Polyhedron, 2014, 70, 172–179 (front page)
· "Synthesis, characterization and biological activity of antimony(III) or bismuth(III) chloride complexes with dithiocarbamate ligands derived fromthiuram degradation", I.I. Ozturk, C.N. Banti, N. Kourkoumelis, M.J. Manos, A.J. Tasiopoulos, A.M. Owczarzak, M. Kubicki, S.K. Hadjikakou, Polyhedron, 2014, 67, 89-103
· "Anti-proliferative and anti-tumor activity of silver(I) compounds", Christina N. Banti, Sotiris K. Hadjikakou, Metallomics, 2013, 5, 569-596
· "Structural and In Vitro Biological Studies of Organotin(IV) Precursors; Selective Inhibitory Activity Against Human Breast Cancer Cells, Positive to Estrogen Receptors", V.I. Balas, C.N. Banti, N. Kourkoumelis, S.K. Hadjikakou, G.D. Geromichalos, D. Sahpazidou, L. Male, M.B. Hursthouse, B. Bednarz, M. Kubicki, K. Charalabopoulos, N. Hadjiliadis, Aust. J. Chem. 2012, 65, 1625–1637 (Research front)
· "Synthesis, structural characterization and in vitro inhibitory studies against human breast cancer of the bis-(2,6-di-tert-butylphenol)tin(IV) dichloride and its complexes", D.B. Shpakovsky, C.N. Banti, G. Beaulieu-Houle, N. Kourkoumelis, M. Manoli, M.J. Manos, A.J. Tasiopoulos, S.K. Hadjikakou, E.R. Milaeva, K. Charalabopoulos, T. Bakas, I.S. Butler, N. Hadjiliadis, Dalton Trans., 2012, 41, 14568
· "Mixed ligand–silver(I) complexes with anti-inflammatory agents which can bind to lipoxygenase and calf-thymus DNA, modulating their function and inducing apoptosis", C.N. Banti, A.D. Giannoulis, N. Kourkoumelis, A.M. Owczarzak, M. Poyraz, M. Kubicki, K. Charalabopoulos, S.K. Hadjikakou, Metallomics, 2012, 4, 545–560, (Front Page)
· "Synthesis, structural characterization and cytotoxicity of the antimony(III) chloride complex with N,N-Dicyclohexyldithiooxamide", I.I. Ozturk, O.S. Urgut, C.N. Banti, N. Kourkoumelis, A.M. Owczarzak, M. Kubicki, K. Charalabopoulos, S.K. Hadjikakou, Polyhedron, 2013, 52, 1403-1410
· "Synthesis, characterization and biological studies of new antimony(III) halide complexes with ω-thiocaprolactam", I.I. Ozturk, C.N. Banti, M.J. Manos, A.J. Tasiopoulos, N. Kourkoumelis, K. Charalabopoulos, S.K. Hadjikakou, J. Inorg. Biochem. 2012, 109, 57–65, (The Target Selection team of Global Medical Discovery identified it to be of special interest of to the drug development sector)
· "Synthesis, structural characterization and biological studies of novel mixed ligand Ag(I) complexes with triphenylphosphine and aspirin or salicylic acid.", M. Poyraz, C.N. Banti, N. Kourkoumelis, V. Dokorou, M.J. Manos, M. Simčič, S. Golič-Grdadolnik, T. Mavromoustakos, A.D. Giannoulis, I.I. Verginadis, K. Charalabopoulos, S.K.Hadjikakou, Inorg. Chim. Acta., 2011, 375, 114–121
1 Protocol published
Evaluation of Genotoxicity by Micronucleus Assay in vitro and by Allium cepa Test in vivo
Authors:  Christina N. Banti and Sotiris K. Hadjikakou, date: 07/20/2019, view: 621, Q&A: 0
The in vitro and in vivo genotoxicity of new metallodrugs either as Small Bioactive Molecules (SBAMs) or Conjugates of Metals with Drugs (CoMeDs) is evaluated by the micronucleus test and the Allium cepa assay, ...
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