Davide Ragozzino Dept. of Physiology and Pharmacology "V. Erspamer", Sapienza University, Italy, Italy,
1 protocol

Silvia Di Angelantonio Dept. of Physiology and Pharmacology "V. Erspamer", Sapienza University, Italy, Italy,
1 protocol

Barbara Cortese Sapienza University
1 protocol

Bernadette Basilico Dept of Physiology and Pharmacology, Sapienza University, Italy, Italy,
1 protocol

Patrizia Ratano
  • Dept. of Physiology and Pharmacology "V. Erspamer", Sapienza University, Italy, Italy,
Research focus
  • Neuroscience
  • 1 Author merit


PhD, Sapienza University of Rome, Italy

Current position

Post-doc, NANOTEC Institute, CNR, Italy


  1. Ratano P., Petrella C., Petrocchi Passeri C., Palmery M., Trezza V., Severini C., Campolongo P., Pharmacological inhibition of 2-arachidonoilglycerol hydrolysis enhances memory consolidation in rats through CB2 receptor activation and mTOR signaling modulation. Neuropharmacology. 2018 May 26. pii: S0028-3908(18)30265-X. doi: 10.1016/j.neuropharm.2018.05.030  
  2. Esposito E., Drechsler M., Mariani P., Carducci F., Servadio M., Melancia F., Ratano P, Campolongo P., Trezza V., Cortesi R., Nastruzzi C., Lipid nanoparticles for administration of poorly water soluble neuroactive drugs. Biomed Microdevices., 2017 Sep;19(3):44. doi: 10.1007/s10544-017-0188-x. 
  3. Ratano P., Palmery M. Trezza V., Campolongo P., Cannabinoid modulation of memory consolidation in rats: beyond the role of cannabinoid receptor subtype 1. Frontiers in Pharmacology, 2017 Apr 12;8:200. doi: 10.3389/fphar.2017.00200. eCollection 2017.  
  4. Merlo E., Ratano P., Ilioi E. C., Robbins M.A.L.S., Everitt B.J.& Milton A.L, Amygdala dopamine receptors are required for the destabilization of a reconsolidating appetitive memory. eNeuro, 2015 DOI: 10.1523/ENEURO.0024-14.2015 
  5. Esposito E.; Ravani L.; Drechsler M.; Mariani P.; Contado C.; Ratano P.; Campolongo P.; Trezza V.; Nastruzzi C.; Cortesi R., Cannabinoid antagonist in nanostructured lipid carriers (NLC): design, characterization and in vivo study. Materials Science and Engineering C, 2015 Mar; 48:328-36.  
  6. Morena M., Roozendaal B., Trezza V., Ratano P., Peloso A., Hauer D., Atsak P. Trabace L., Cuomo V., McGaugh J.L., Schelling G., Campolongo P., Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training. PNAS, 2014 Dec, 111(51):18333-8. 
  7. Scuderi C., Stecca C., Valenza M., Ratano P., Bronzuoli M.R., Bartoli S., Steardo L., Pompili E., Fumagalli L., Campolongo P. And Steardo L., Palmitoylethanolamide controls reactive gliosis and exerts neuroprotective functions in a rat model of Alzheimer’s disease. Cell Death & Disease 2014 Sep, 5:e1419; doi:10.1038/cddis.2014.376.  
  8. Ratano P., Everitt B.J., Milton A.L., The CB1 receptor antagonist AM251 impairs reconsolidation of pavlovian fear memory in the rat basolateral amygdala, Neuropsychopharmacology 2014 Oct, 39 (11):2529-37. 
  9. Campolongo P.*, Ratano P.*,Ciotti M.T., Florenzano F., Marolda R., Palmery M., Possenti R., Rinaldi A.M., Calissano P. and Severini C., Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: Involvement of Kv potassium channels, Plos One 2013 Nov 12;8(11):e78036. doi: 10.1371/journal.pone.0078036, 
  10. *Equal Contribution. Milton A.L., Merlo E., Ratano P., Gregory B.L., Dumbreck J.K., Everitt B.J., Double dissociation of the requirement for GluN2B-and GluN2A-containing NMDA receptors in the destabilization and restabilization of a reconsolidating memory, J Neurosci. 2013 Jan 16;33(3):1109-15. doi: 10.1523/JNEUROSCI.3273-12.2013. 
  11. Campolongo P.*, Ratano P.*, Manduca A., Scattoni M.L., Palmery M., Trezza V., Cuomo V., The endocannabinoid transport inhibitor AM404 differentially modulates recognition memory in rats depending on environmental aversiveness, Front Behav Neurosci. 2012;6:11, 
  12. *Equal Contribution. Hauer D., Ratano P., Morena M., Briegel I., Scaccianoce S., Palmery M., Cuomo V., Roozendaal B., Schelling G., Campolongo P., Propofol Enhances Long-Term Memory Formation via an Interaction with the Endocannabinoid System, Anesthesiology. 2011 Jun;114(6):1380-8.  
  13. Campolongo P, Trezza V., Ratano P., Palmery M., Cuomo V., Developmental consequences of perinatal cannabis exposure: behavioral and neuroendocrine effects in adult rodents, Psychopharmacology, 2010 Mar;214(1):5-15.
1 Protocol published
Time-lapse Whole-field Fluorescence Imaging of Microglia Processes Motility in Acute Mouse Hippocampal Slices and Analysis
Microglia are the resident immune cells of the central nervous system (CNS). In the last year, the improvements in the transgenic mouse technologies and imaging techniques have shed light on microglia functions under physiological conditions. ...
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