Feng Yang Division of Life Science, Hong Kong University of Science and Technology, Hong Kong
1 protocol

Xiao Tang Division of Life Science, Hong Kong University of Science and Technology, Hong Kong
1 protocol

Yusong Guo
  • Assistant Professor, Division of Life Science, Hong Kong University of Science and Technology, 2015-
Research focus
  • -
  • 1 Author merit


PhD, Carnegie Mellon University, USA, 2008


• Huang, Y., Ma, T., Lau, P. K., Wang, J., Zhao, T., Du, S., Loy, M. M. T. and Guo, Y. (2019). Visualization of Protein Sorting at the Trans-Golgi Network and Endosomes Through Super-Resolution Imaging. Front Cell Dev Biol 7: 181.
• Niu, L., Ma, T., Yang, F., Yan, B., Tang, X., Yin, H., Wu, Q., Huang, Y., Yao, Z. P., Wang, J., Guo, Y. and Hu, J. (2019). Atlastin-mediated membrane tethering is critical for cargo mobility and exit from the endoplasmic reticulum. Proc Natl Acad Sci U S A 116(28): 14029-14038.
• Mao, Y., Tu, R., Huang, Y., Mao, D., Yang, Z., Lau, P. K., Wang, J., Ni, J., Guo, Y. and Xie, T. (2019). The exocyst functions in niche cells to promote germline stem cell differentiation by directly controlling EGFR membrane trafficking. Development 146(13).
• Huang, Y., Ma, T. and Guo, Y. (2018). Intracellular trafficking of planar cell polarity proteins. Frontiers in Biology 13.
• Ma, T., Li, B., Wang, R., Lau, P., Huang, Y., Jiang, L., Schekman, R. and Guo, Y. (2018). A mechanism for differential sorting of the planar cell polarity proteins Frizzled6 and Vangl2 at the trans-Golgi network. J Biol Chem 293: jbc.RA118.001906.
• Guo, Y., Yang, F. and Tang, X. (2017). An Overview of Protein Secretion in Yeast and Animal Cells. Methods Mol Biol 1662: 1-17.
• Ma, Y., Feng, L., Guo, Y. and Gong, H. (2016). Statistical analysis and probabilistic verification of stress-induced signalling pathways. Int J Data Min Bioin14: 120.
• Guo, Y., Sirkis, D. W. and Schekman, R. (2014). Protein sorting at the trans-Golgi network. Annu Rev Cell Dev Biol 30: 169-206.
• Guo, Y., Zanetti, G. and Schekman, R. (2013). A novel GTP-binding protein-adaptor protein complex responsible for export of Vangl2 from the trans Golgi network. Elife 2: e00160.
• Guo, Y. and Linstedt, A. D. (2013). Binding of the vesicle docking protein p115 to the GTPase Rab1b regulates membrane recruitment of the COPI vesicle coat. Cell Logist 3: e27687.
• Gong, H., Guo, Y., Linstedt, A. and Schwartz, R. (2010). Discrete, continuous, and stochastic models of protein sorting in the Golgi apparatus. Phys Rev E Stat Nonlin Soft Matter Phys 81(1 Pt 1): 011914.
• Srinivasa, G., Fickus, M. C., Guo, Y., Linstedt, A. D. and Kovačević, J. (2009). Active mask segmentation of fluorescence images. IEEE Transactions on Image Processing 18(8):1817-1829.
• Guo, Y., Punj, V., Sengupta, D. and Linstedt, A. D. (2008). Coat-tether interaction in Golgi organization. Mol Biol Cell 19(7): 2830-2843.
• Srinivasa, G., Fickus, M., Gonzalez-Rivero, M., Hsieh, S., Guo, Y., Linstedt, A. and Kovacevic, J. (2008). Active mask segmentation for the cell-volume computation and Golgi-body segmentation of hela cell images.
• Guo, Y. and Linstedt, A. (2006). COPII–Golgi protein interactions regulate COPII coat assembly and Golgi size. J cell biol 174: 53-63.
• Guo, Y., Kong, L., Wang, Y. and Huang, Z. (2004). Antidepressant evaluation of polysaccharides from a Chinese herbal medicine Banxia-houpu decoction. Phytotherapy Research 18(3), 204-207.
• Kong, L., Yang, C., Ge, F., Wang, H. and Guo, Y. (2004). A Chinese herbal medicine Ermiao wan reduces serum uric acid level and inhibits liver xanthine dehydrogenase and xanthine oxidase in mice. Journal of ethnopharmacology 93: 325-330.
1 Protocol published
Cell-free Reconstitution of the Packaging of Cargo Proteins into Vesicles at the trans Golgi Network
Authors:  Xiao Tang, Feng Yang and Yusong Guo, date: 03/05/2020, view: 761, Q&A: 0
Protein sorting at the trans Golgi network (TGN) plays important roles in targeting newly synthesized proteins to their specific destinations. The aim of this proposal is to reconstitute the packaging of non-Golgi resident cargo proteins ...
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