Walter Sandtner Department of Pharmacology, Medical University of Vienna, Austria, Austria,
1 protocol

Matej Hotka Department of Pharmacology, Medical University of Vienna, Austria, Austria,
1 protocol

Verena Burtscher
  • Institute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Austria, Austria,
  • 1 Author merit

Education

PhD, Medical University of Vienna, Austria

Current position

Postdoc, Pharmacology and Physiology, Medical University of Vienna, Austria

Publications

  1. Burtscher V, Hotka M, Li Y, Freissmuth M, Sandtner W. (2018): A label-free approach to detect ligand binding to cell surface proteins in real time. Elife 7. pii: e34944. doi: 10.7554/eLife.34944.
  2. Li Y, Mayer FP, Hasenhuetl PS, Burtscher V, Schicker K, Sitte HH, Freissmuth M, Sandtner W. (2017): Occupancy of the zinc-binding site by transition metals decreases the substrate affinity of the human dopamine transporter by an allosteric mechanism. J Biol Chem. 292 (17): 7161. doi: 10.1074/jbc.A116.760140.
  3. Bacchi N, Messina A, Burtscher V, Dassi E, Provenzano G, Bozzi Y, Demontis GC, Koschak A, Denti MA, Casarosa S. (2015): A New Splicing Isoform of Cacna2d4 Mimicking the Effects of c.2451insC Mutation in the Retina: Novel Molecular and Electrophysiological Insights. Invest Ophthalmol Vis Sci. 56 (8): 4846-56. doi: 10.1167/iovs.15-16410. 
  4. Burtscher V, Schicker K, Novikova E, Pöhn B, Stockner T, Kugler C, Singh A, Zeitz C, Lancelot ME, Audo I, Leroy BP, Freissmuth M, Herzig S, Matthes J, Koschak A. (2014): Spectrum of Cav1.4 dysfunction in congenital stationary night blindness type 2. Biochim Biophys Acta.1838 (8): 2053-65. doi: 10.1016/j.bbamem.2014.04.023.
  5. Etemad S, Obermair GJ, Bindreither D, Benedetti A, Stanika R, Di Biase V, Burtscher V, Koschak A, Kofler R, Geley S, Wille A, Lusser A, Flockerzi V, Flucher BE. (2014): Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression. J Neurosci. 34 (4): 1446-61. doi: 10.1523/JNEUROSCI.3935-13.2014.
1 Protocol published
Detection of Ligand-binding to Membrane Proteins by Capacitance Measurements
Authors:  Verena Burtscher, Matej Hotka and Walter Sandtner, date: 01/05/2019, view: 155, Q&A: 0
In multi-cellular organisms, cells communicate with each other utilizing chemical messengers. For many of these messenger molecules, the membrane is an insurmountable barrier. Yet, they act by binding to surface proteins often triggering a cascade ...
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