Reviewer
Xie Liwei
  • Faculty, Guangdong Institute of Microbiology
Research focus
  • Molecular biology
  • Stem cell, metabolic diseases, and microbiome

Education

Ph.D., University of Florida, 2013

Lab information

Research Group for Gut Microbiome and Health (RGGMH)

Publications

1. L. Xie, J.F. Collins, Transcriptional regulation of the Menkes copper ATPase (Atp7a) gene by hypoxia-inducible factor (HIF2 ) in intestinal epithelial cells, AJP Cell Physiol. 300 (2011) C1298–C1305.
2. L. Xie, J.F. Collins, Copper stabilizes the Menkes copper-transporting ATPase (Atp7a) protein expressed in rat intestinal epithelial cells, AJP Cell Physiol. 304 (2013) C257–C262.
3. L. Xie, J.F. Collins, Transcription Factors Sp1 and Hif2 Mediate Induction of the Copper-transporting ATPase (Atp7a) Gene in Intestinal Epithelial Cells during Hypoxia, J. Biol. Chem. 288 (2013) 23943–23952.
4. L. Xie, X. Xue, M. Taylor, S.K. Ramakrishnan, K. Nagaoka, C. Hao, F.J. Gonzalez, Y.M. Shah, Hypoxia-Inducible Factor/MAZ-Dependent Induction of Caveolin-1 Regulates Colon Permeability through Suppression of Occludin, Leading to Hypoxia-Induced Inflammation, Mol. Cell. Biol. 34 (2014) 3013–3023.
5. W. Qin, X. Li, L. Xie, S. Li, J. Liu, L. Jia, X. Dong, X. Ren, J. Xiao, C. Yang, Y. Zhou, Z. Chen, A long non-coding RNA, APOA4 -AS, regulates APOA4 expression depending on HuR in mice, Nucleic Acids Res. 44 (2016) 6423–6433.
6. C. Cao, T. Zhang, D. Zhang, L. Xie, X. Zou, L. Lei, D. Wu, L. Liu, The long non-coding RNA, SNHG6-003, functions as a competing endogenous RNA to promote the progression of hepatocellular carcinoma., Oncogene. (2016).
, L. Xie, Hypoxia-Inducible Factors Link Iron Homeostasis and Erythropoiesis, Gastroenterology. 146 (2014) 630–642.
8. C. Cao, J. Sun, D. Zhang, X. Guo, L. Xie, X. Li, D. Wu, L. Liu, The Long Intergenic Noncoding RNA UFC1, a Target of MicroRNA 34a, Interacts With the mRNA Stabilizing Protein HuR to Increase Levels of β-Catenin in HCC Cells, Gastroenterology. 148 (2015) 415–426.e18.
9. E.R. Anderson, M. Taylor, X. Xue, S.K. Ramakrishnan, A. Martin, L. Xie, B.X. Bredell, S. Gardenghi, S. Rivella, Y.M. Shah, Intestinal HIF2 promotes tissue-iron accumulation in disorders of iron overload with anemia, Proc. Natl. Acad. Sci. 110 (2013) E4922–E4930.
10. N. Das, L. Xie, S.K. Ramakrishnan, A. Campbell, S. Rivella, Y.M. Shah, Intestine-specific Disruption of Hypoxia-inducible Factor (HIF)-2α Improves Anemia in Sickle Cell Disease, J. Biol. Chem. 290 (2015) 23523–23527.
11. L. Gan, L. Xie, F. Zuo, Z. Xiang, N. He, Transcriptomic analysis of Rongchang pig brains and livers, Gene. 560 (2015) 96–106.
12. H. Zhang, Q. Chen, T. Jiao, A. Cui, X. Sun, W. Fang, L. Xie, Y. Liu, F. Fang, Y. Chang, Involvement of KLF11 in Hepatic Glucose Metabolism in Mice via Suppressing of PEPCK-C Expression, PLoS One. 9 (2014) e89552.
13. X. Xue, S.K. Ramakrishnan, K. Weisz, D. Triner, L. Xie, D. Attili, A. Pant, B. Győrffy, M. Zhan, C. Carter-Su, K.M. Hardiman, T.D. Wang, M.K. Dame, J. Varani, D. Brenner, E.R. Fearon, Y.M. Shah, Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis, Cell Metab. 24 (2016) 447–461.
14. L. Wang, X. Tong, F. Gu, L. Zhang, W. Chen, X. Cheng, L. Xie, Y., Chang, and H. Zhang, The KLF14 Transcription Factor Regulates Hepatic Gluconeogenesis in Mice. Journal of Biological Chemistry 292 (52):21631–42.
15. X. Zhu, Q. Kong, L. Xie, Z. Chen, H. Li, Z. Zhu, Y. Huang, F. Lan, H. Luo, J. Zhan, H. Ding, J. Lei, Q. Xiao, W. Fu, W. Fan, J. Zhang, H. Luo. The single-nucleotide polymorphisms in CHD5 affect the prognosis of patients with hepatocellular carcinoma. Oncotarget. In Press 2017.
16. L. Zhang, Y. Chen, W. Cheng, W. Li, J. Chen,G. Xu, L. Xie. Effect of dietary histamine levels on growth performance and body pigmentation of Pelteobagrus fulvidraco. Freshwater Fisheries, 2017, 47(5): 79-84
17. L. Xie, A. Yin, A.S. Nichenko, A.M. Beedle, J.A. Call, H.Yin, Transient HIF2 Inhibition Accelerates Muscle Regeneration by Promoting Satellite Cell Proliferation. J Clin Invest. 2018 Jun 1;128(6):2339-2355.
18. W. Li, X. Pan, W. Chen, Y. Yin, J. Chen, G. Xu, L. Xie. Serum biochemistry, histology and transcriptomic profile analysis reflect liver inflammation and damage following dietary histamine supplementation in yellow catfish (Pelteobagrus fulvidraco). Fish Shellfish Immuno. 2018 Mar 20;77:83-90
19. G. Chen, B. Huang, S. Fu, B. Li, X. Ran, D. He, L. Jiang, Y. Li, B. Liu, L. Xie, J. Liu, W. Wang. G Protein-Coupled Receptor 109A and Host Microbiota Modulate Intestinal Epithelial Integrity During Sepsis. Front Immunol. 2018 Sep 13;9:2079(IF: 4.9共同通讯作者)
20. X. Tong, Q. Zhang, L. Wang, Y. Ji, L. Zhang, L. Xie, W. Chen, H. Zhang. RNF186 impairs insulin sensitivity by inducing ER stress in mouse primary hepatocytes. Cell Signal. 2018 Dec;52:155-162
21. Y. Long, S. Li, J. Qin, L. Xie, L. Gan, F. Jie, Y. Wu, Y. Li, Q. Du. Kuijieling regulates the differentiation of Treg and Th17 cells to ameliorate experimental colitis in rats. Biomed Pharmacother. 2018 Sep;105:781-788
22. X. Li, L. Jia, X. Chen, Y. Dong, X. Ren, Y. Dong, Y. Chen, L. Xie, M. Liu, C. Shiota, G.K. Gittes, L. Rui, Z. Chen. Islet-cell inflammation induced by NF-kB Indcuing kinase (NIK) leads to hypoglycemia, pancreatitis,growth retardation and postnatal death in mice. Theranostics. 2018;8(21):5960-5971.
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