Liwei Xie
  • Dr., Gut Microbiome and Health, Guangdong Institute of Microbiology
Research focus
  • Molecular biology
  • Stem cell, metabolic diseases, and microbiome
  • 1 Author merit


Ph.D., University of Florida, 2013

Lab information

Research Group for Gut Microbiome and Health (RGGMH)


Corresponding Author
· B. Liu, X. Pan, L. Yao, S. Chen, Z. Liu, M. Han, Y. Yin, G. Xu, D. Wan, X. Dai, J. Sun, J. Pan, H. Zhang, W. Wang, L., L. Xie. Fecal microbiota as a non-invasive biomarker to predict the tissue iron accumulation in intestine epithelial cells and liver. bioRxiv.2019. Jan 2019:612168.
· S. Herrlinger, Q. Shao, M, Yang, Q. Chang, Y, Liu, X. Pan, H. Yin, L. Xie, J. Chen. Lin28-mediated promotion of protein synthesis is critical for neural progenitor cell maintenance and brain development in mice. Development, 2019, In Press.
· X. Pan, B. Liu, S. Chen, H. Ding, X. Yao, Y. Cheng, D. Xu, Y. Yin, X. Dai, J. Sun, G. Xu, J. Pan, L. Xiao, L. Xie. Nr4a1 as a myogenic factor is upregulated in satellite cells/myoblast under proliferation and differentiation state. BBRC, 2019 Jun 4;513(3):573-581
· X. Yao, T. Yu, F. Xi, Y. XU, L. Ma, X. Pan, S. Chen, M. Han, Y. Yin, X. Dai, G. Xu, H. Zhang, G. Yang, L. Xie. BAMBI shuttling between cyto and membrane is required for skeletal muscle development and regeneration. BBRC, 2019 Jan 29; 509(1): 125-132
· W. Li, X. Pan, W. Chen, Y. Yin, J. Chen, G. Xu, L. Xie. Serum biochemistry, histology and transcriptomic profile analysis reflect liver inflammation and damage following dietary histamine supplementation in yellow catfish (Pelteobagrus fulvidraco). Fish Shellfish Immuno. 2018 Mar 20;77:83-90
· G. Chen, B. Huang, S. Fu, B. Li, X. Ran, D. He, L. Jiang, Y. Li, B. Liu, L. Xie, J. Liu, W. Wang. G Protein-Coupled Receptor 109A and Host Microbiota Modulate Intestinal Epithelial Integrity During Sepsis. Front Immunol. 2018 Sep 13;9:2079
· X. Tong, Q. Zhang, L. Wang, Y. Ji, L. Zhang, L. Xie, W. Chen, H. Zhang. RNF186 impairs insulin sensitivity by inducing ER stress in mouse primary hepatocytes. Cell Signal. 2018 Dec;52:155-162
· 张丽,成艳波,程炜轩,李薇,陈金涛,谢黎炜*,许国焕. 组胺对黄颡鱼生长及体色变异的影响,淡水渔业,2017,47(5):79-84
· L. Wang, X. Tong, F. Gu, L. Zhang, W. Chen, X. Cheng, L. Xie, Y., Chang, and H. Zhang, The KLF14 Transcription Factor Regulates Hepatic Gluconeogenesis in Mice. Journal of Biological Chemistry 292 (52):21631–42.

First Author
· L. Xie, A. Yin, A.S. Nichenko, A.M. Beedle, J.A. Call, H.Yin, Transient HIF2 Inhibition Accelerates Muscle Regeneration by Promoting Satellite Cell Proliferation. J Clin Invest. 2018 Jun 1;128(6):2339-2355. (IF:12.78)
· L. Xie, X. Xue, M. Taylor, S.K. Ramakrishnan, K. Nagaoka, C. Hao, F.J. Gonzalez, Y.M. Shah, Hypoxia-Inducible Factor/MAZ-Dependent Induction of Caveolin-1 Regulates Colon Permeability through Suppression of Occludin, Leading to Hypoxia-Induced Inflammation, Mol. Cell. Biol. 34 (2014) 3013–3023.
· L. Xie, J.F. Collins, Copper stabilizes the Menkes copper-transporting ATPase (Atp7a) protein expressed in rat intestinal epithelial cells, AJP Cell Physiol. 304 (2013) C257–C262.
· L. Xie, J.F. Collins, Transcription Factors Sp1 and HIF2 Mediate Induction of the Copper-transporting ATPase (Atp7a) Gene in Intestinal Epithelial Cells during Hypoxia, J. Biol. Chem. 288 (2013) 23943–23952.
· L. Xie, J.F. Collins, Transcriptional regulation of the Menkes copper ATPase (Atp7a) gene by hypoxia-inducible factor (HIF2) in intestinal epithelial cells, AJP Cell Physiol. 300 (2011) C1298–C1305.
· W. Qin, X. Li, L. Xie, S. Li, J. Liu, L. Jia, X. Dong, X. Ren, J. Xiao, C. Yang, Y. Zhou, Z. Chen, A long non-coding RNA, APOA4 -AS, regulates APOA4 expression depending on HuR in mice, Nucleic Acids Res. 44 (2016) 6423–6433.
· C. Cao, T. Zhang, D. Zhang, L. Xie, X. Zou, L. Lei, D. Wu, L. Liu, The long non-coding RNA, SNHG6-003, functions as a competing endogenous RNA to promote the progression of hepatocellular carcinoma., Oncogene. (2016).
· X. Zhu, Q. Kong, L. Xie, Z. Chen, H. Li, Z. Zhu, Y. Huang, F. Lan, H. Luo, J. Zhan, H. Ding, J. Lei, Q. Xiao, W. Fu, W. Fan, J. Zhang, H. Luo. The single-nucleotide polymorphisms in CHD5 affect the prognosis of patients with hepatocellular carcinoma. Oncotarget. 2017 Dec 26;9(17):13222-13230.
1 Protocol published
Isolation and Culture of Single Myofiber and Immunostaining of Satellite Cells from Adult C57BL/6J Mice
Authors:  Shujie Chen, Hongrong Ding, Xiangping Yao and Liwei Xie, date: 07/20/2019, view: 4729, Q&A: 0
Myofiber isolation followed with ex vivo culture could recapitulate and visualize satellite cells (SCs) activation, proliferation, and differentiation. This approach could be taken to understand the physiology of satellite cells and the ...
We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.