Yoshishige Miyabe
  • Faculty, Nippon Medical School
Research focus
  • Immunology
  • Rheumatology, Immunology, Intravital Imaging




1. Sadik CK, Miyabe Y, Sezin T, Luster AD. "The critical role of C5a as an initiator of neutrophil-mediated autoimmune inflammation of the joint and skin." Seminars in Immunology. 2018: 37:21.
2. Sorensen EW, Lian J, Ozga A, Miyabe Y, Ji S, Bromley SK, Mempel TR, Luster AD. "CXCL10 stabilizes T cell-brain endothelial cell adhesion leading to the induction of cerebral malaria." JCI Insight. 2018: 3(8). pii: 98911.
3. Angelini A, Miyabe Y, Newsted D, Kwan HB, Miyabe C, Kelly RL, Jamy NM, Luster AD, Wittrup DK. "Directed evolution of proteins with exceptional biding promiscuity and superior therapeutic efficacy." Nature Communications. 2018: 9(1):1461.
4. Miyabe Y, Miyabe C, Luster AD. "LTB4 and BLT1 in inflammatory arthritis." Seminars in Immunology. 2017: 33: 52-57.
5. Miyabe Y, Miyabe C, Murooka TT, Kim YE, Newton GA, Kim ND, Haribabu B, Luscinskas FW, Mempel TR, Luster AD. "Complement C5a Receptor is the Key Initiator of Neutrophil Adhesion Igniting Immune Complex-induced Arthritis." Science Immunology. 2017: 2: eaaj 2195.
6. Miyabe C, Miyabe Y, Komiya T, Shioya H, Miura NN, Takahashi K, Ohno N, Tsuboi R, Luster AD, Kawai S, Nanki T. "A sphingosine 1-phosphate receptor agonist ameliorates animal model of vasculitis." Inflammation Research. 2017: 66: 335-340.
7. Miyabe C, Miyabe Y, Strle K, Kim ND, Stone JH, Luster AD, and Unizony S. "An expanded population of pathogenic regulatory T-cells in giant cell arteritis is abrogated by IL-6 blockade therapy." Annals of Rheumatic Diseases. 2017: 76: 898-905.
8. Miyabe Y, Kim ND, Miyabe C, Luster AD. "Studying Neutrophil Migration In Vivo Using Adoptive Cell Transfer." Methods in Molecular Biology. 2016; 1407: 179-94.
9. Miyabe Y, Kim ND, Miyabe C, Luster AD. "Studying Chemokine Control of Neutrophil Migration In Vivo in a Murine Model of Inflammatory Arthritis." Methods in Enzymology. 2016; 570: 207-31.
10. Miyabe Y, Miyabe C, Nanki T. "Could retinoids be a potential treatment for rheumatic diseases?" Rheumatology International. 2015; 35: 35-41.
11. Miyabe Y, Miyabe C, Iwai Y, Yokoyama W, Sekine C, Sugimoto K, Harigai M, Miyasaka M, Miyasaka N, Nanki T. "Activation of fibroblast-like synoviocytes derived from rheumatoid arthritis via lysophosphatidic acid-lysophosphatidic acid receptor 1 cascade." Arthritis Research and Therapy. 2014; 16(5): 461.
12. Yokoyama W, Kohsaka H, Kaneko K, Walters M, Takayasu A, Fukuda S, Miyabe C, Miyabe Y, Love PE, Nakamoto N, Kanai T, Watanabe-Imai K, Charvat TT, Penfold ME, Jaen J, Schall TJ, Harigai M, Miyasaka N, Nanki T. "Abrogation of CC chemokine receptor 9 ameliorates collagen-induced arthritis of mice." Arthritis Research and Therapy. 2014; 16(5): 445.
13. Fukuda S, Kohsaka H, Takayasu A, Yokoyama W, Miyabe C, Miyabe Y, Harigai M, Miyasaka N, Nanki T. "Cannabinoid receptor 2 as a potential therapeutic target in rheumatoid arthritis." BMC Musculoskeletal Disorders. 2014; 15: 275.
14. Miyabe Y, Miyabe C, Iwai Y, Takayasu A, Fukuda S, Yokoyama W, Nagai J, Jona M, Tokuhara Y, Ohkawa R, Albers HM, Ovaa H, Aoki J, Chun J, Yatomi Y, Ueda H, Miyasaka M, Miyasaka N, Nanki T. "Necessity of lysophosphatidic acid receptor 1 for development of arthritis." Arthritis and Rheumatology. 2013; 65: 2037-47.
15. Takayasu A, Miyabe Y, Yokoyama W, Kaneko K, Fukuda S, Miyasaka N, Miyabe C, Kubota T, Nanki T. "CCL18 activates fibroblast-like synoviocytes in patients with rheumatoid arthritis." The Journal of Rheumatology. 2013; 40: 1026-8.
16. Miyabe C, Miyabe Y, Miura NN, Takahashi K, Terashima Y, Toda E, Honda F, Morio T, Yamagata N, Ohno N, Shudo K, Suzuki J, Isobe M, Matsushima K, Tsuboi R, Miyasaka N, Nanki T. "Am80, a retinoic acid receptor agonist, ameliorates murine vasculitis through the suppression of neutrophil migration and activation." Arthritis and Rheumatology. 2013; 65: 503-12.
17. Takenaka K, Miyabe Y, Kasai S, Matsumoto T, Nagasaka K. [Polymyositis in a father and his son; a case report]. Nihon rinsho meneki gakkaishi. 2012: 35: 144-9.
18. Kaneko K, Miyabe Y, Takayasu A, Fukuda S, Miyabe C, Ebisawa M, Yokoyama W, Watanabe K, Imai T, Muramoto K, Terashima Y, Sugihara T, Matsushima K, Miyasaka N, Nanki T. "Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis." Arthritis Research and Therapy. 2011; 13: R158.
19. Nonomura Y, Miyabe Y, Tanaka M, Tsubata R, Nanki T, Harigai M, Miyasaka N. “Prominent splenic microcalcifications in a patient with systemic lupus erythematosus complicated by antiphospholipid syndrome.” Journal of Clinical Rheumatology. 2011: 17: 288.
20. Miyabe Y, Murata Y, Baba Y, Ito E, Nagasaka K. “Successful treatment of cyclosporine-A-resistant cytophagic histiocytic panniculitis with tacrolimus.” Modern Rheumatology. 2011: 21: 553-6.
21. Yamazaki H, Miyabe Y, Tomoishi J, Kawai S, Ito E, Nagasaka K. “Microscopic polyangiitis with renal mass-like lesion: a case report.” Nihon rinsho meneki gakkaishi. 2011: 34: 162-7.
22. Watanabe K, Penfold ME, Matsuda A, Ohyanagi N, Kaneko K, Miyabe Y, Matsumoto K, Schall TJ, Miyasaka N, Nanki T. “Pathogenic role of CXCR7 in rheumatoid arthritis.” Arthritis and Rheumatology. 2010: 62: 3211-20.
23. Okada R, Miyabe Y, Kasai S, Hashimoto K, Yamauchi S, Yoshikawa M, Sumori K, Nagasaka K. “Successful treatment of interstitial pneumonia and pneumomediastinum associated with polymyositis during pregnancy with a combination of cyclophosphamide and tacrolimus: A case report.” Nihon rinsho meneki gakkaishi. 2010: 33: 142-8.
We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.