Damarais Magdalene Pediatric Ophthalmology, Sri Sankaradeva Nethralaya, India, India,
1 protocol

Darilang Mawrie Biosciences and Bioengineering, Indian Institute of Technology Guwahati, India, India,
1 protocol

Amit Sharma Biosciences and Bioengineering, Indian Institute of Technology Guwahati, India, India,
1 protocol

Bithiah Grace Jaganathan
  • Biosciences and Bioengineering, Indian Institute of Technology Guwahati, India, India,
  • 1 Author merit


PhD, Johann Wolfgang Goethe University, Germany

Current position

Associate Professor, Biosciences and Bioengineering, Indian Institute of Technology Guwahati, India


  1. Chinnapaka Somaiah, Atul Kumar, Renu Sharma, Amit Sharma, Trishna Anand, Jina Bhattacharyya, Damodar Das, Sewali Deka Talukdar, Bithiah Grace Jaganathan. Mesenchymal stem cells show functional defect and decreased anti-cancer effect after exposure to chemotherapeutic drugs. J Biomed Sci. 2018; 25: 5. doi: 10.1186/s12929-018-0407-7 
  2. Atul Kumar, Trishna Anand, Jina Bhattacharyya, Amit Sharma, Bithiah Grace Jaganathan. K562 chronic myeloid leukemia cells modify osteogenic differentiation and gene expression of bone marrow stromal cells.. J. Cell Commun. Signal. (2017). https://doi.org/10.1007/s12079-017-0412-8. 
  3. Atul Kumar, Jina Bhattacharyya, Bithiah Grace Jaganathan. Adhesion to stromal cells mediates imatinib resistance in chronic myeloid leukemia through ERK and BMP signaling pathways. Scientific Reports 7, 9535 (2017). doi:10.1038/s41598-017-10373-3. 
  4. Atul Kumar, Anshuman Bhanja, Jina Bhattacharyya, Bithiah Grace Jaganathan. Multiple roles of CD90 in cancer. Tumor Biol. (2016) 37: 11611. https://doi.org/10.1007/s13277-016-5112-0. 
  5. Darilang Mawrie, Atul Kumar, Damaris Magdalene, Jina Bhattacharyya, Bithiah Grace Jaganathan. Mesenchymal stem cells from human extra ocular muscle harbor neuroectodermal differentiation potential. 2016. PLoS One 11(6): e0156697. doi:10.1371/journal.pone.0156697. 
  6. Chinnapaka Somaiah, Atul Kumar, Darilang Mawrie, Amit Sharma, Suraj Patil, Jina Bhattacharyya, R. Swaminathan, Bithiah Grace Jaganathan. Collagen promotes higher adhesion, survival and proliferation of mesenchymal stem cells.. 2015. PLoS One 10(12): e0145068. doi:10.1371/journal.pone.0145068. 
  7. Himangshu Sonowal, Atul Kumar, Jina Bhattacharyya, Pabitra Kumar Gogoi, Bithiah Grace Jaganathan. Inhibition of actin polymerization decreases osteogeneic differentiation of mesenchymal stem cells through p38 MAPK pathway.. J Biomed Sci. 2013 Sep 26;20(1):71. 
  8. Bithiah Grace Jaganathan, Fernando Anjos-Afonso, Atul Kumar, Dominique Bonnet. Active RHOA favors retention of human hematopoietic stem/progenitor cells in the niche.. J Biomed Sci. 2013 Sep 11;20(1):66. doi: 10.1186/1423-0127-20-66. 
  9. Bithiah Grace Jaganathan, Dominique Bonnet. Human Mesenchymal Stem Cells Senesce with Exogenous OCT4. Cytotherapy. 2012 Oct;14(9):1054-63. doi: 10.3109/14653249.2012.697145. Effects of MSC co-injection on the reconstitution of aplastic anemia patient following hematopoietic stem cell transplantation. Bithiah Grace Jaganathan, Veronica Tisato, Thomas Vulliamy, Inderjeet Dokal, Judith Marsh, Francesco Dazzi, Dominique Bonnet. Leukemia. 2010 Oct;24(10):1791-5. doi: 10.1038/leu.2010.164. [Abstract] 
  10. Bithiah Grace Jaganathan, Brigitte Ruester, Lars Dressel, Stefan Stein, Manuel Grez, Erhard Seifried, Reinhard Henschler. Rho inhibition induces migration of mesenchymal stromal cells. Stem Cells. 2007 Aug;25(8):1966-74. 
  11. Stephan Gottig, Dietrich Moebest, Brigitte Ruster, Bithiah Grace, Sylvia Winter, Erhard Seifried, Jens Gille, Thomas Wieland, Reinhard Henschler. Role of monomeric GTPase Rho in hematopoietic progenitor cell migration and transplantation. Eur J Immunol. Jan 2006, Vol. 36, Issue 1:180-9. 
  12. Brigitte Ruester, Bithiah Grace, Oliver Seitz, Erhard Seifried, Reinhard Henschler. Induction and Detection of Human Mesenchymal Stem Cell Migration in the 48-Well Reusable Transwell Assay. Stem Cells Dev. 2005 Apr;14(2):231-5.
1 Protocol published
Isolation of Multipotent Mesenchymal Stem Cells from Human Extraocular Muscle Tissue
Authors:  Amit Sharma, Darilang Mawrie, Damarais Magdalene and Bithiah Grace Jaganathan, date: 02/20/2019, view: 1239, Q&A: 0
Mesenchymal stem cells (MSCs) have attracted significant attention as potential therapeutic cells to treat various diseases ranging from tissue injuries, graft versus host disease, degenerative diseases and cancer. Since the initial discovery of ...
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