Olivier Binda Université Claude Bernard Lyon 1
1 protocol

Karl Riabowol Department of Biochemistry and Molecular Biology and Department of Oncology, University of Calgary, Canada, Canada,
1 protocol

Lisa Butler 1 protocol

Urszula McClurg 1 protocol

Stuart R McCracken
  • Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, England, England,
Research focus
  • Cancer biology
  • 1 Author merit


PhD, Newcastle University, England, 2008

Current position

Senior Lecturer and Honorary Consultant in Urology Newcastle University and Sunderland Royal Hospital, England


  1. McClurg, U. L., Chit, N., Azizyan, M., Edwards, J., Nabbi, A., Riabowol, K. T., Nakjang, S., McCracken, S. R. and Robson, C. N. (2018). Molecular mechanism of the TP53-MDM2-AR-AKT signalling network regulation by USP12. Oncogene 37(34): 4679-4691. 
  2. McClurg, U. L., Nabbi, A., Ricordel, C., Korolchuk, S., McCracken, S., Heer, R., Wilson, L., Butler, L. M., Irving-Hooper, B. K., Pedeux, R., Robson, C. N., Riabowol, K. T. and Binda, O. (2018). Human ex vivo prostate tissue model system identifies ING3 as an oncoprotein. Br J Cancer 118(5): 713-726.
  3. McClurg, U. L., Harle, V. J., Nabbi, A., Batalha-Pereira, A., Walker, S., Coffey, K., Gaughan, L., McCracken, S. R. and Robson, C. N. (2015). Ubiquitin-specific protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer. Oncotarget 6(35): 37724-37736. 
  4. Gao, M., Patel, R., Ahmad, I., Fleming, J., Edwards, J., McCracken, S., Sahadevan, K., Seywright, M., Norman, J., Sansom, O. and Leung, H. Y. (2012). SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis. EMBO Mol Med 4(8): 776-790.
  5. Ramsay, A. K., McCracken, S. R., Soofi, M., Fleming, J., Yu, A. X., Ahmad, I., Morland, R., Machesky, L., Nixon, C., Edwards, D. R., Nuttall, R. K., Seywright, M., Marquez, R., Keller, E. and Leung, H. Y. (2011). ERK5 signalling in prostate cancer promotes an invasive phenotype. Br J Cancer 104(4): 664-672.
  6. Gaughan, L., Stockley, J., Wang, N., McCracken, S. R., Treumann, A., Armstrong, K., Shaheen, F., Watt, K., McEwan, I. J., Wang, C., Pestell, R. G. and Robson, C. N. (2011). Regulation of the androgen receptor by SET9-mediated methylation. Nucleic Acids Res 39(4): 1266-1279.
1 Protocol published
Ex vivo Culture and Lentiviral Transduction of Benign Prostatic Hyperplasia (BPH) Samples
Authors:  Urszula Lucja McClurg, Stuart R McCracken, Lisa Butler, Karl T Riabowol and Olivier Binda, date: 11/05/2018, view: 3205, Q&A: 0
To assess oncogenic potential, classical transformation assays are based on cell line models. However, cell line based models do not reflect the complexity of human tissues. We thus developed an inducible expression system for gene expression in ex ...
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