Shuiying Hu Pharmaceutics & Pharmaceutical Chemistry, The Ohio State University, USA, USA,
1 protocol

Mingqing Chen Pharmaceutics & Pharmaceutical Chemistry, The Ohio State University, USA, USA,
1 protocol

Jason Anderson Pharmaceutics & Pharmaceutical Chemistry, The Ohio State University, USA, USA,
1 protocol

Muhammad Uddin Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, USA, USA,
1 protocol

Alix F. Leblanc
  • Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, USA, USA,
  • 1 Author merit

Education

Ph.D. in toxicology, Université Paris Descartes UFR Biomédicale, 2014

Current position

Postdoctoral research fellow, Ohio State University, Columbus, OH, USA

Publications

  1. Leblanc, A. F., Sprowl, J. A., Alberti, P., Chiorazzi, A., Arnold, W. D., Gibson, A. A., Hong, K. W., Pioso, M. S., Chen, M., Huang, K. M., Chodisetty, V., Costa, O., Florea, T., de Bruijn, P., Mathijssen, R. H., Reinbolt, R. E., Lustberg, M. B., Sucheston-Campbell, L. E., Cavaletti, G., Sparreboom, A. and Hu, S. (2018). OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity. J Clin Invest 128(2): 816-825.
  2. Attignon, E. A., Distel, E., Le-Grand, B., Leblanc, A. F., Barouki, R., de Oliveira, E., Aggerbeck, M. and Blanc, E. B. (2017). Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of alpha-endosulfan and dioxin in HepaRG human cells. Toxicol In Vitro 45(Pt 3): 309-317.
  3. Hu, S., Leblanc, A. F., Gibson, A. A., Hong, K. W., Kim, J. Y., Janke, L. J., Li, L., Vasilyeva, A., Finkelstein, D. B., Sprowl, J. A., Sweet, D. H., Schlatter, E., Ciarimboli, G., Schellens, J., Baker, S. D., Pabla, N. and Sparreboom, A. (2017). Identification of OAT1/OAT3 as Contributors to Cisplatin Toxicity. Clin Transl Sci 10(5): 412-420.
  4. Duval, C., Teixeira-Clerc, F., Leblanc, A. F., Touch, S., Emond, C., Guerre-Millo, M., Lotersztajn, S., Barouki, R., Aggerbeck, M. and Coumoul, X. (2017). Chronic Exposure to Low Doses of Dioxin Promotes Liver Fibrosis Development in the C57BL/6J Diet-Induced Obesity Mouse Model. Environ Health Perspect 125(3): 428-436.
  5. Attignon, E. A., Leblanc, A. F., Le-Grand, B., Duval, C., Aggerbeck, M., Rouach, H. and Blanc, E. B. (2017). Novel roles for AhR and ARNT in the regulation of alcohol dehydrogenases in human hepatic cells. Arch Toxicol 91(1): 313-324.
  6. Guyot, E., Solovyova, Y., Tomkiewicz, C., Leblanc, A., Pierre, S., El Balkhi, S., Le Frere-Belda, M. A., Lecuru, F., Poupon, J., Barouki, R., Aggerbeck, M. and Coumoul, X. (2015). Determination of Heavy Metal Concentrations in Normal and Pathological Human Endometrial Biopsies and In Vitro Regulation of Gene Expression by Metals in the Ishikawa and Hec-1b Endometrial Cell Line. PLoS One 10(11): e0142590.
  7. Ambolet-Camoit, A., Ottolenghi, C., Leblanc, A., Kim, M. J., Letourneur, F., Jacques, S., Cagnard, N., Guguen-Guillouzo, C., Barouki, R. and Aggerbeck, M. (2015). Two persistent organic pollutants which act through different xenosensors (alpha-endosulfan and 2,3,7,8 tetrachlorodibenzo-p-dioxin) interact in a mixture and downregulate multiple genes involved in human hepatocyte lipid and glucose metabolism. Biochimie 116: 79-91.
  8. Ambolet-Camoit, A., Kim, M. J., Leblanc, A. and Aggerbeck, M. (2012). Les polluants organiques persistants: implication dans l’obésité et le syndrome métabolique. Cahiers de Nutrition et de Diététique  47(4):183–192.
1 Protocol published
Murine Pharmacokinetic Studies
Murine pharmacokinetics (PK) represents the absorption, distribution, metabolism, and elimination of drugs from the body, which helps to guide clinical studies, ultimately resulting in more effective drug treatment. The purpose of this protocol is ...
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